iEEG‐recon: a fast and scalable pipeline for accurate reconstruction of intracranial electrodes and implantable devices

A Lucas, BH Scheid, AR Pattnaik, R Gallagher… - …, 2024 - Wiley Online Library
Objective Clinicians use intracranial electroencephalography (iEEG) in conjunction with
noninvasive brain imaging to identify epileptic networks and target therapy for drug‐resistant …

Atypical connectome topography and signal flow in temporal lobe epilepsy

K Xie, J Royer, S Larivière, R Rodriguez-Cruces… - Progress in …, 2024 - Elsevier
Temporal lobe epilepsy (TLE) is the most common pharmaco-resistant epilepsy in adults.
While primarily associated with mesiotemporal pathology, recent evidence suggests that …

[HTML][HTML] Subcortical functional connectivity gradients in temporal lobe epilepsy

A Lucas, S Mouchtaris, EJ Cornblath, N Sinha… - NeuroImage: Clinical, 2023 - Elsevier
Abstract Background and Motivation Functional gradients have been used to study
differences in connectivity between healthy and diseased brain states, however this work …

Subject-based assessment of large-scale integration dynamics in epileptic brain networks: insights from the intrinsic ignition framework

A Donaire, N Padilla, A Escrichs, M Khawja… - Cerebral …, 2024 - academic.oup.com
This study examined the dynamic properties of brain regions involved in the genesis and
spread of seizures in 10 individuals diagnosed with pharmacoresistant focal epilepsy. The …

Interictal intracranial EEG asymmetry lateralizes temporal lobe epilepsy

EC Conrad, A Lucas, WKS Ojemann… - Brain …, 2024 - academic.oup.com
Patients with drug-resistant temporal lobe epilepsy often undergo intracranial EEG recording
to capture multiple seizures in order to lateralize the seizure onset zone. This process is …

Dynamic reconfiguration of aperiodic brain activity supports cognitive functioning in epilepsy: A neural fingerprint identification

ET Lopez, MC Corsi, A Danieli, L Antoniazzi… - iScience, 2025 - cell.com
Temporal lobe epilepsy (TLE) is characterized by alterations of brain dynamic on a large-
scale associated with altered cognitive functioning. Here, we aimed at analyzing dynamic …

Closed-loop electrical stimulation to prevent focal epilepsy progression and long-term memory impairment

JJ Ferrero, AR Hassan, Z Yu, Z Zhao, L Ma, C Wu… - bioRxiv, 2024 - biorxiv.org
Interictal epileptiform discharges (IEDs) are ubiquitously expressed in epileptic networks
and disrupt cognitive functions. It is unclear whether addressing IED-induced dysfunction …

[HTML][HTML] Improved seizure onset-zone lateralization in temporal lobe epilepsy using 7T resting-state fMRI: A direct comparison with 3T

A Lucas, EJ Cornblath, N Sinha, L Caciagli, P Hadar… - medRxiv, 2023 - ncbi.nlm.nih.gov
Objective: Resting-state functional magnetic resonance imaging (rs-fMRI) at ultra high-field
strengths (≥ 7T) is known to provide superior signal-to-noise and statistical power than …

Dynamic reconfiguration of aperiodic brain activity supports cognitive functioning in epilepsy: a neural fingerprint identification

E Troisi Lopez, MC Corsi, A Danieli, L Antoniazzi… - medRxiv, 2024 - medrxiv.org
Background Temporal lobe epilepsy (TLE) is characterized by alterations of brain dynamic
at large scale associated with altered cognitive functioning. Interindividual variability of brain …

Connectivity of the Piriform Cortex and its Implications in Temporal Lobe Epilepsy

A Lucas, M Jaskir, N Sinha, A Pattnaik… - medRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Background: The piriform cortex has been implicated in the initiation, spread and termination
of epileptic seizures. This understanding has extended to surgical management of epilepsy …