Discontinuation, suboptimal adherence, and reinitiation of oral HIV pre-exposure prophylaxis: a global systematic review and meta-analysis

J Zhang, C Li, J Xu, Z Hu, SE Rutstein, JD Tucker… - The lancet HIV, 2022 - thelancet.com
Background Poor adherence to oral HIV pre-exposure prophylaxis (PrEP) diminishes its
clinical and public health benefits. This study synthesises evidence regarding …

Effects of pre-exposure prophylaxis for the prevention of human immunodeficiency virus infection on sexual risk behavior in men who have sex with men: a systematic …

MW Traeger, SE Schroeder, EJ Wright… - Clinical Infectious …, 2018 - academic.oup.com
Background Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) is
effective in reducing HIV risk in men who have sex with men (MSM). However, concerns …

Emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): primary results from a …

KH Mayer, JM Molina, MA Thompson, PL Anderson… - The Lancet, 2020 - thelancet.com
Background Tenofovir alafenamide shows high antiviral efficacy and improved renal and
bone safety compared with tenofovir disoproxil fumarate when used for HIV treatment. Here …

[HTML][HTML] The prevalence of pre-exposure prophylaxis use and the pre-exposure prophylaxis–to-need ratio in the fourth quarter of 2017, United States

AJ Siegler, F Mouhanna, RM Giler, K Weiss… - Annals of …, 2018 - Elsevier
Purpose The number of individuals who have started a regimen for HIV pre-exposure
prophylaxis (PrEP) in the United States is not well characterized but has been on the rise …

Population-level effectiveness of rapid, targeted, high-coverage roll-out of HIV pre-exposure prophylaxis in men who have sex with men: the EPIC-NSW prospective …

AE Grulich, R Guy, J Amin, F Jin, C Selvey, J Holden… - The lancet HIV, 2018 - thelancet.com
Background HIV pre-exposure prophylaxis (PrEP) is highly effective in men who have sex
with men (MSM) at the individual level, but data on population-level impact are lacking. We …

Post-exposure prophylaxis with doxycycline to prevent sexually transmitted infections in men who have sex with men: an open-label randomised substudy of the …

JM Molina, I Charreau, C Chidiac, G Pialoux… - The Lancet Infectious …, 2018 - thelancet.com
Background Increased rates of sexually transmitted infections (STIs) have been reported
among men who have sex with men. We aimed to assess whether post-exposure …

HIV preexposure prophylaxis: a review

J Riddell, KR Amico, KH Mayer - Jama, 2018 - jamanetwork.com
Importance About 40 000 Americans and 2 million people worldwide are newly infected with
HIV each year. The combination antiretroviral regimen, tenofovir disoproxil fumarate …

A systematic review of adherence to oral pre-exposure prophylaxis for HIV–how can we improve uptake and adherence?

D Sidebottom, AM Ekström, S Strömdahl - BMC infectious diseases, 2018 - Springer
Introduction Oral pre-exposure prophylaxis (PrEP) is an effective strategy to reduce the risk
of HIV transmission in high risk individuals. However, the effectiveness of oral pre-exposure …

[HTML][HTML] Trends in the use of oral emtricitabine/tenofovir disoproxil fumarate for pre-exposure prophylaxis against HIV infection, United States, 2012–2017

PS Sullivan, RM Giler, F Mouhanna, ES Pembleton… - Annals of …, 2018 - Elsevier
Abstract Purpose Pre-exposure prophylaxis (PrEP) with oral emtricitibine/tenofovir disoproxil
fumarate (TDF/FTC) reduces the risk of HIV infection by> 90% when taken as prescribed …

Sexual behaviour and incidence of HIV and sexually transmitted infections among men who have sex with men using daily and event-driven pre-exposure prophylaxis …

E Hoornenborg, L Coyer, RCA Achterbergh… - The lancet HIV, 2019 - thelancet.com
Summary Background Pre-exposure prophylaxis (PrEP) for HIV might induce risk
compensation, defined as increased sexual risk behaviour leading to increased incidence of …