Ebola virus disease in humans: pathophysiology and immunity

C Muñoz-Fontela, AK McElroy - Marburg-and ebolaviruses: From …, 2017 - Springer
Viruses of the Ebolavirus genus cause sporadic epidemics of severe and systemic febrile
disease that are fueled by human-to-human transmission. Despite the notoriety of …

Drug repurposing for Ebola virus disease: principles of consideration and the animal rule

JPF Bai, CW Hsu - Journal of Pharmaceutical Sciences, 2019 - Elsevier
There are no approved drugs or biologics to treat Ebola virus disease (EVD). Literature
reviews identified a list of 141 drugs with reports of preliminary in vitro potency and in vivo …

[HTML][HTML] Depletion of Bone Marrow Hematopoietic Cells in Ebolavirus-Infected Rhesus Macaques: A Possible Cause of Hematologic Abnormalities in Ebolavirus …

DX Liu, B Pahar, DL Perry, H Xu, TK Cooper… - The American Journal of …, 2023 - Elsevier
The pathophysiology of long-recognized hematologic abnormalities in Ebolavirus (EBOV)
disease (EVD) is unknown. From limited human sampling (of peripheral blood), it has been …

Ebola infection in pregnancy: a global perspective and lessons learned

LB Haddad, J Horton, BS Ribner… - Clinical obstetrics and …, 2018 - journals.lww.com
The 2014 to 2016 Ebola outbreak, primarily based in 3 West African countries, had far-
reaching global effects. Importantly, the crisis highlighted large gaps in reproductive health …

High-containment pathogen preparation in the intensive care unit

BT Garibaldi, DS Chertow - Infectious Disease Clinics, 2017 - id.theclinics.com
The recent Ebola virus disease (EVD) outbreak in West Africa in 2014 to 2016 highlighted
the capabilities of dedicated biocontainment units (BCUs) at the National Institutes of Health …

Impact of intensive care unit supportive care on the physiology of Ebola virus disease in a universally lethal non-human primate model

G Poliquin, D Funk, S Jones, K Tran… - Intensive care medicine …, 2019 - Springer
Background There are currently limited data for the use of specific antiviral therapies for the
treatment of Ebola virus disease (EVD). While there is anecdotal evidence that supportive …

Clinical management of patients with Ebola virus disease in high-resource settings

G Marshall Lyon, AK Mehta, BS Ribner - Marburg-and Ebolaviruses: From …, 2017 - Springer
Like most viral illnesses in humans, supportive care of the patient is the mainstay of clinical
care for patients with Ebola virus disease (EVD). The goal is to maintain and sustain the …

[PDF][PDF] Reemergência em saúde do vírus Ebola: uma revisão Ebola virus health reemergency: a review

T da Silva Carvalho, FC Ferreira… - Brazilian Journal of …, 2021 - scholar.archive.org
RESUMO O EBOV representa um dos vírus mais perigosos e mortais que existe a nível
mundial, podendo afetar os humanos e determinados animais, como por exemplo os …

A Retrospective Analysis of Ebola Virus Disease in Liberia

MJ Matson - 2022 - search.proquest.com
The outbreak of Ebola virus disease (EVD) centered in the West African countries of Guinea,
Liberia, and Sierra Leone from 2013-2016 was the longest and largest such outbreak on …

[HTML][HTML] A Couple with Different Symptoms after Simultaneously 2019-nCoV Infected

Y Zhang, H Tang, J Li, F Zhang, J Chen, F Wang, S Lin… - 2020 - europepmc.org
Background: 2019-nCoV has posed a significant threat to human health since the epidemic
began. So far, there is no definite safe and effective drug treatment. Proper management can …