As the “chemical chameleon”, sulfonyl-containing compounds and their variants have been
merged with various types of reactions for the efficient construction of diverse molecular …

Although carbon is the central element of organic chemistry, oxygen is the central element of
stereoelectronic control in organic chemistry. Generally, a molecule with a C–O bond has …

The selective synthesis of N 2-sulfonyl and N 2-H 1, 2, 3-triazoles via organocatalytic
annulation of enaminone/enaminoester with sulfonyl azide has been realized. The …

Diverse strategies for the efficient and attractive synthesis of a wide variety of relevant 1, 4, 5-
trisubstituted 1, 2, 3-triazole molecules are reported. The synthesis of this category of diverse …

Proteolysis-targeting chimeras (PROTACs) are a powerful approach for targeted protein
degradation. One of the current bottlenecks for developing PROTACs is the lack of an …

An efficient iodide ion (I−)-enabled method for direct α-C (sp3)–H triazolization of ethers via
a radical cross-coupling has been developed for regioselective construction of N2 …

A regioselective electrochemical C–H amination method to synthesize N 2-substituted 1, 2, 3-
triazole using easily accessible ethers has been developed. Various substituents, including …

The C (sp2)–H function of indole ketone with diazo compound via a rhodium (II)-catalyzed
intramolecular electrophilic trapping reaction under mild conditions in air was demonstrated …

Immediately after the invention of 'Click Chemistry'in 2002, the regioselective 1, 2, 3-triazole
scaffolds resulted from respective organic azides and terminal alkynes under Cu (I) catalysis …

Chemotherapy combining with surgical treatment has been the main strategy for
osteosarcoma treatment in clinical. Due to unclear pathogenesis and unidentified drug …