Excessive sugar consumption is increasingly considered as a contributor to the emerging
epidemics of obesity and the associated cardiometabolic disease. Sugar is added to the diet …

Absorption of monosaccharides is mainly mediated by Na+-d-glucose cotransporter SGLT1
and the facititative transporters GLUT2 and GLUT5. SGLT1 and GLUT2 are relevant for …

The heart is adapted to utilize all classes of substrates to meet the high-energy demand, and
it tightly regulates its substrate utilization in response to environmental changes. Although …

The number of known glucose transporters has expanded considerably over the past 2
years. At least three, and up to six, Na+-dependent glucose transporters (SGLT1–SGLT6; …

Facilitative glucose transport is mediated by members of the Glut protein family that belong
to a much larger superfamily of 12 transmembrane segment transporters. Six members of …

Glucose is the major energy source for mammalian cells as well as an important substrate
for protein and lipid synthesis. Mammalian cells take up glucose from extracellular fluid into …

Glucose is the principle energy source for the mammalian brain. Delivery of glucose from the
blood to the brain requires transport across the endothelial cells of the blood‐brain barrier …

In this review we summarize the present state of knowledge of the currently identified
members of the glucose transporter family, propose a basis for their diversity highlighting …

We recently reported that the glucose transporter isoform, GLUT5, is expressed on the brush
border membrane of human small intestinal enterocytes (Davidson, NO, Hausman, AML …

Insulin receptors are known to be located on nerve cells in mammalian brain. The binding of
insulin to dimerized receptors stimulates specialized transporter proteins that mediate the …