Traumatic brain injury: progress and challenges in prevention, clinical care, and research
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
An update on diagnostic and prognostic biomarkers for traumatic brain injury
Introduction: Traumatic brain injury (TBI) is a major worldwide neurological disorder of
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …
Advances in the development of biomarkers for epilepsy
Over 50 million people worldwide have epilepsy. In nearly 30% of these cases, epilepsy
remains unsatisfactorily controlled despite the availability of over 20 antiepileptic drugs …
remains unsatisfactorily controlled despite the availability of over 20 antiepileptic drugs …
Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
Executive summary A concerted effort to tackle the global health problem posed by traumatic
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …
Neuroinflammation in animal models of traumatic brain injury
Traumatic brain injury (TBI) is a leading cause of mortality and morbidity worldwide.
Neuroinflammation is prominent in the short and long-term consequences of neuronal …
Neuroinflammation is prominent in the short and long-term consequences of neuronal …
Association of blood biomarkers with acute sport-related concussion in collegiate athletes: findings from the NCAA and Department of Defense CARE Consortium
M McCrea, SP Broglio, TW McAllister, J Gill… - JAMA network …, 2020 - jamanetwork.com
Importance There is potential scientific and clinical value in validation of objective
biomarkers for sport-related concussion (SRC). Objective To investigate the association of …
biomarkers for sport-related concussion (SRC). Objective To investigate the association of …
Serial sampling of serum protein biomarkers for monitoring human traumatic brain injury dynamics: a systematic review
Background The proteins S100B, neuron-specific enolase (NSE), glial fibrillary acidic
protein (GFAP), ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), and neurofilament light …
protein (GFAP), ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), and neurofilament light …
Incremental prognostic value of acute serum biomarkers for functional outcome after traumatic brain injury (CENTER-TBI): an observational cohort study
Background Several studies have reported an association between serum biomarker values
and functional outcome following traumatic brain injury. We aimed to examine the …
and functional outcome following traumatic brain injury. We aimed to examine the …
A serum protein biomarker panel improves outcome prediction in human traumatic brain injury
E Thelin, F Al Nimer, A Frostell, H Zetterberg… - Journal of …, 2019 - liebertpub.com
Brain-enriched protein biomarkers of tissue fate are being introduced clinically to aid in
traumatic brain injury (TBI) management. The aim of this study was to determine how …
traumatic brain injury (TBI) management. The aim of this study was to determine how …
Blood biomarkers for brain injury: What are we measuring?
K Kawata, CY Liu, SF Merkel, SH Ramirez… - Neuroscience & …, 2016 - Elsevier
Accurate diagnosis for mild traumatic brain injury (mTBI) remains challenging, as prognosis
and return-to-play/work decisions are based largely on patient reports. Numerous …
and return-to-play/work decisions are based largely on patient reports. Numerous …