Applications, promises, and pitfalls of deep learning for fluorescence image reconstruction

C Belthangady, LA Royer - Nature methods, 2019 - nature.com
Deep learning is becoming an increasingly important tool for image reconstruction in
fluorescence microscopy. We review state-of-the-art applications such as image restoration …

Active matter at the interface between materials science and cell biology

D Needleman, Z Dogic - Nature reviews materials, 2017 - nature.com
The remarkable processes that characterize living organisms, such as motility, self-healing
and reproduction, are fuelled by a continuous injection of energy at the microscale. The field …

Odd dynamics of living chiral crystals

TH Tan, A Mietke, J Li, Y Chen, H Higinbotham… - Nature, 2022 - nature.com
Active crystals are highly ordered structures that emerge from the self-organization of motile
objects, and have been widely studied in synthetic, and bacterial, active matter. Whether …

Nonequilibrium physics in biology

X Fang, K Kruse, T Lu, J Wang - Reviews of Modern Physics, 2019 - APS
Life is characterized by a myriad of complex dynamic processes allowing organisms to grow,
reproduce, and evolve. Physical approaches for describing systems out of thermodynamic …

Hydrodynamic theory of active matter

F Jülicher, SW Grill, G Salbreux - Reports on Progress in Physics, 2018 - iopscience.iop.org
We review the general hydrodynamic theory of active soft materials that is motivated in
particular by biological matter. We present basic concepts of irreversible thermodynamics of …

Cellular chirality arising from the self-organization of the actin cytoskeleton

YH Tee, T Shemesh, V Thiagarajan, RF Hariadi… - Nature cell …, 2015 - nature.com
Cellular mechanisms underlying the development of left–right asymmetry in tissues and
embryos remain obscure. Here, the development of a chiral pattern of actomyosin was …

Transition from turbulent to coherent flows in confined three-dimensional active fluids

KT Wu, JB Hishamunda, DTN Chen, SJ DeCamp… - Science, 2017 - science.org
INTRODUCTION Conventional nonequilibrium systems are composed of inanimate
components whose dynamics is powered by the external input of energy. For example, in a …

The actin cytoskeleton as an active adaptive material

S Banerjee, ML Gardel… - Annual review of …, 2020 - annualreviews.org
Actin is the main protein used by biological cells to adapt their structure and mechanics to
their needs. Cellular adaptation is made possible by molecular processes that strongly …

Coordination of morphogenesis and cell-fate specification in development

CJ Chan, CP Heisenberg, T Hiiragi - Current Biology, 2017 - cell.com
During animal development, cell-fate-specific changes in gene expression can modify the
material properties of a tissue and drive tissue morphogenesis. While mechanistic insights …

Global morphogenetic flow is accurately predicted by the spatial distribution of myosin motors

SJ Streichan, MF Lefebvre, N Noll, EF Wieschaus… - Elife, 2018 - elifesciences.org
During embryogenesis tissue layers undergo morphogenetic flow rearranging and folding
into specific shapes. While developmental biology has identified key genes and local …