Although the currently available pharmacological assays can cure most pathological
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …

Gut microbiota has become a topical issue in unraveling the research mechanisms
underlying disease onset and progression. As an important and potential “organ,” gut …

Damage-induced fibrotic scarring limits tissue regeneration in mammals and is a leading
cause of morbidity. In contrast, species like zebrafish can regenerate damaged tissues …

Background: Certain nonmammalian species such as zebrafish have an elevated capacity
for innate heart regeneration. Understanding how heart regeneration occurs in these …

The extent of tissue regeneration varies widely between species. Mammals have a limited
regenerative capacity whilst lower vertebrates such as the zebrafish (Danio rerio), a …

Despite considerable efforts carried out to develop stem/progenitor cell-based technologies
aiming at replacing and restoring the cardiac tissue following severe damages, thus far no …

Cardiac development is characterized by the active proliferation of different cardiac cell
types, in particular cardiomyocytes and endothelial cells, that eventually build the beating …

Cardiovascular diseases are the leading cause of death worldwide, among which ischemic
heart disease is the most representative. Myocardial infarction results from occlusion of a …

Kyphomelic dysplasia is a rare heterogenous group of skeletal dysplasia, characterized by
bowing of the limbs, severely affecting femora with distinct facial features. Despite its first …

Spinal motor nerves are necessary for organismal locomotion and survival. In zebrafish and
most vertebrates, these peripheral nervous system structures are composed of bundles of …