The aim of this systematic review is to give an update of all currently available evidence on
the relevance of a geriatric assessment in the treatment of older patients with hematologic …

Importance Acute myeloid leukemia (AML) is a clonal hematopoietic cancer that disrupts
normal hematopoiesis, ultimately leading to bone marrow failure and death. The annual …

Frailty, defined as an age-related state of increased vulnerability to acute stressors, is a
major challenge in the care of older people with haematological malignancies. Growing …

Summary In 2020, about 600 000 people aged 65 years and older were diagnosed with a
haematological malignancy worldwide, and this number will increase to almost 1 million by …

Background and objective The prognostic value of age and other non-hematological factors
in predicting outcomes in older patients with newly diagnosed acute myeloid leukemia …

With the introduction of targeted chemotherapy drugs, a new age of treatment for acute
myeloid leukemia (AML) has begun. The promotion of the azacitidine+ venetoclax …

Acute myeloid leukemia (AML) is a disease primarily affecting older adults. However, not all
patients at older ages are suitable for curative treatment with intensive chemotherapy due to …

Introduction This study aims to develop and validate a simple score to estimate survival in
the older population suffering from malignant hemopathies. Methods We prospectively …

Introduction: Treating acute myeloid leukemia (AML) in older adults remains daunting. The
unique biology often renders conventional chemotherapies less effective. Accurately …

Background Frailty is a state of increased vulnerability to stressors, and predicts risk of
adverse outcomes, such as mortality. Frailty can be defined by a frailty index (FI) using an …