[HTML][HTML] The value of real world evidence: the case of medical cannabis

AK Schlag, RR Zafar, MT Lynskey, LD Phillips… - Frontiers in …, 2022 - frontiersin.org
Randomised controlled trials (RCTs) have long been considered the gold standard of
medical evidence. In relation to cannabis based medicinal products (CBMPs), this focus on …

Assessment of clinical outcomes of medicinal cannabis therapy for depression: analysis from the UK Medical Cannabis Registry

S Mangoo, S Erridge, C Holvey… - Expert review of …, 2022 - Taylor & Francis
Background Although pre-clinical experiments associate cannabinoids with reduced
depressive symptoms, there is a paucity of clinical evidence. This study aims to analyze the …

Medicinal cannabis improves sleep in adults with insomnia: a randomised double‐blind placebo‐controlled crossover study

K Ried, T Tamanna, S Matthews… - Journal of sleep …, 2023 - Wiley Online Library
Insomnia or difficulty falling and or staying asleep is experienced by up to 30% of the
general population. This randomised crossover double‐blind placebo‐controlled 6‐week …

Multinational Association of Supportive Care in Cancer (MASCC) guidelines: cannabis for psychological symptoms including insomnia, anxiety, and depression

G De Feo, AA Case, GB Crawford, D Hui, J To… - Supportive Care in …, 2023 - Springer
Purpose During the treatment of cancer, 18% of patients use cannabis for symptom
management. Anxiety, depression, and sleep disturbances are common symptoms in …

An updated analysis of clinical outcome measures across patients from the UK Medical Cannabis Registry

M Ergisi, S Erridge, M Harris, M Kawka… - Cannabis and …, 2023 - liebertpub.com
Introduction: There is a growing body of literature supporting the efficacy of cannabis-based
medicinal products (CBMPs). Despite an increase in prescribing globally, there is a paucity …

A Randomized, Double-Blind, Placebo-Controlled Decentralized Trial to Assess Sleep, Health Outcomes, and Overall Well-Being in Healthy Adults Reporting …

A Kolobaric, SJ Hewlings, C Bryant, CS Colwell… - Nutrients, 2023 - mdpi.com
Inadequate sleep is a global health concern. Sleep is multidimensional and complex; new
multi-ingredient agents are needed. This study assessed the comparative effects of two multi …

[HTML][HTML] Cannabinoids: Emerging sleep modulator

ZXB Low, XR Lee, T Soga, BH Goh, D Alex… - Biomedicine & …, 2023 - Elsevier
Sleep is an essential biological phase of our daily life cycle and is necessary for maintaining
homeostasis, alertness, metabolism, cognition, and other key functions across the animal …

Cannabinoids, insomnia, and other sleep disorders

I Lavender, IS McGregor, A Suraev, RR Grunstein… - Chest, 2022 - Elsevier
Sleep disturbances are often cited as a primary reason for medicinal cannabis use, and
there is increasing clinical interest in the therapeutic potential of cannabinoids in treating …

A double-blind, randomized, placebo-controlled study of the safety and effects of CBN with and without CBD on sleep quality.

MO Bonn-Miller, MT Feldner, TM Bynion… - Experimental and …, 2024 - psycnet.apa.org
The present study sought to determine the effects of cannabinol (CBN) alone and in
combination with cannabidiol (CBD) on sleep quality. This was a double-blind, randomized …

[HTML][HTML] A large Australian longitudinal cohort registry demonstrates sustained safety and efficacy of oral medicinal cannabis for at least two years

AW Vickery, S Roth, T Ernenwein, J Kennedy… - PLoS one, 2022 - journals.plos.org
Introduction Oral medicinal cannabis (MC) has been increasingly prescribed for a wide
range of clinical conditions since 2016. Despite an exponential rise in prescriptions and …