Hydrogels: properties and applications in biomedicine

TC Ho, CC Chang, HP Chan, TW Chung, CW Shu… - Molecules, 2022 - mdpi.com
Hydrogels are crosslinked polymer chains with three-dimensional (3D) network structures,
which can absorb relatively large amounts of fluid. Because of the high water content, soft …

Bioactive materials promote wound healing through modulation of cell behaviors

R Li, K Liu, X Huang, D Li, J Ding, B Liu… - Advanced …, 2022 - Wiley Online Library
Skin wound repair is a multistage process involving multiple cellular and molecular
interactions, which modulate the cell behaviors and dynamic remodeling of extracellular …

3D extracellular matrix mimics: fundamental concepts and role of materials chemistry to influence stem cell fate

J Nicolas, S Magli, L Rabbachin, S Sampaolesi… - …, 2020 - ACS Publications
Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

Tumor angiogenesis and anti-angiogenic strategies for cancer treatment

RI Teleanu, C Chircov, AM Grumezescu… - Journal of clinical …, 2019 - mdpi.com
Angiogenesis is the process through which novel blood vessels are formed from pre-existing
ones and it is involved in both physiological and pathological processes of the body …

Tumor-on-a-chip: from bioinspired design to biomedical application

X Liu, J Fang, S Huang, X Wu, X Xie, J Wang… - Microsystems & …, 2021 - nature.com
Cancer is one of the leading causes of human death, despite enormous efforts to explore
cancer biology and develop anticancer therapies. The main challenges in cancer research …

Advanced drug delivery systems and artificial skin grafts for skin wound healing

HS Kim, X Sun, JH Lee, HW Kim, X Fu… - Advanced drug delivery …, 2019 - Elsevier
Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …

Chitosan-based inks for 3D printing and bioprinting

M Taghizadeh, A Taghizadeh, MK Yazdi, P Zarrintaj… - Green …, 2022 - pubs.rsc.org
The advent of 3D-printing/additive manufacturing in biomedical engineering field has
introduced great potential for the preparation of 3D structures that can mimic native tissues …

3D bioprinting of engineered tissue flaps with hierarchical vessel networks (VesselNet) for direct host‐to‐implant perfusion

AA Szklanny, M Machour, I Redenski… - Advanced …, 2021 - Wiley Online Library
Engineering hierarchical vasculatures is critical for creating implantable functional thick
tissues. Current approaches focus on fabricating mesoscale vessels for implantation or …

Ice templating soft matter: fundamental principles and fabrication approaches to tailor pore structure and morphology and their biomedical applications

H Joukhdar, A Seifert, T Jüngst, J Groll… - Advanced …, 2021 - Wiley Online Library
Porous scaffolds are widely used in biomedical applications where pore size and
morphology influence a range of biological processes, including mass transfer of solutes …

Design challenges in polymeric scaffolds for tissue engineering

MI Echeverria Molina, KG Malollari… - … in Bioengineering and …, 2021 - frontiersin.org
Numerous surgical procedures are daily performed worldwide to replace and repair
damaged tissue. Tissue engineering is the field devoted to the regeneration of damaged …