Polypharmacy prevalence in older adults seen in United States physician offices from 2009 to 2016

EH Young, S Pan, AG Yap, KR Reveles, K Bhakta - PLoS One, 2021 - journals.plos.org
Background/objectives With an aging population suffering from increased prevalence of
chronic conditions in the United States (US), a large portion of these patients are on multiple …

Drug repurposing: re-inventing therapies for cancer without re-entering the development pipeline—a review

S Siddiqui, AJ Deshmukh, P Mudaliar… - Journal of the Egyptian …, 2022 - Springer
While majority of the current treatment approaches for cancer remain expensive and are
associated with several side effects, development of new treatment modalities takes a …

Evaluation of anti-inflammatory activity of Justicia secunda Vahl leaf extract using in vitro and in vivo inflammation models

GN Anyasor, AA Okanlawon, B Ogunbiyi - Clinical Phytoscience, 2019 - Springer
Abstract Background Justicia secunda Vahl. is a medicinal plant used in ethnomedical
practice as therapy to manage inflammation. Therefore, this study was designed to evaluate …

Bio-prospective of Acidophile Microorganisms in Biodegradation of NSAIDs

A Ratnasari, IF Zainiyah, SS Thakur… - Current Pollution …, 2024 - Springer
The presence of nonsteroidal anti-inflammatory drugs (NSAIDs) in various environments
poses a significant challenge due to their widespread volume, complexity, and harmful …

A mechanistic study on the inhibition of bacterial growth and inflammation by Nerium oleander extract with comprehensive in vivo safety profile

Y Shafiq, SBS Naqvi, GH Rizwani, MA Asghar… - … medicine and therapies, 2021 - Springer
Background Nerium oleander (L.) is well known traditionally used medicinal plant with
several pharmacological activities. However, the anti-bacterial, anti-inflammatory activity and …

Optimizing Nimesulide Loaded Cubosomal Gel for Enhanced Efficacy: A Systematic Engineering Approach with Factorial Design for Topical Applications

V Deshmukh, YV Pore, R Shikalgar… - Journal of …, 2024 - Springer
Purpose The primary aim of this study is to develop a cubosome nanoformulation for the
optimized delivery of nimesulide, with a focus on improving its efficacy and reducing adverse …

Minimising Harm and Managing Pain: Deprescribing Opioids in Older Adults

AV Langford, CR Schneider, E Reeve, D Gnjidic - Drugs & Aging, 2024 - Springer
Approximately one in three older adults (aged 65 years and over) experience pain,
negatively impacting their quality of life. Opioid analgesics are commonly prescribed to …

Patterns of Comorbidities and Prescribing and Dispensing of Non-steroidal Anti-inflammatory Drugs (NSAIDs) Among Patients with Osteoarthritis in the USA: Real …

J Ide, A Shoaibi, K Wagner, R Weinstein, KE Boyle… - Drugs & Aging, 2024 - Springer
Background Osteoarthritis (OA) is a major cause of chronic pain. Non-steroidal anti-
inflammatory drugs (NSAIDs) are analgesics commonly used for musculoskeletal pain; …

Care of Geriatric Trauma Patients

PD Magidson, A Derry-Ehrler - Current Geriatrics Reports, 2024 - Springer
Abstract Purpose of Review The older adult population is increasing and with growth in this
demographic, there is a rise in the number of geriatric trauma patients requiring care. Older …

Recent Insights and Clinical Status on Novel Mefenamic Acid Nanocarriers for the Treatment of Rheumatoid Arthritis

S Tyagi, MS Pande, M Islam - Current Nanomaterials, 2024 - benthamdirect.com
Joint structure and performance can be compromised by the systemic inflammatory disorder
rheumatoid arthritis, which destroys articular cartilage and erodes periarticular bone …