Advances in anti-tumor treatments targeting the CD47/SIRPα axis

W Zhang, Q Huang, W Xiao, Y Zhao, J Pi, H Xu… - Frontiers in …, 2020 - frontiersin.org
CD47 is an immunoglobulin that is overexpressed on the surface of many types of cancer
cells. CD47 forms a signaling complex with signal-regulatory protein α (SIRPα), enabling the …

Teichoic acids and related cell-wall glycopolymers in Gram-positive physiology and host interactions

C Weidenmaier, A Peschel - Nature Reviews Microbiology, 2008 - nature.com
Abstract Abstract| Most Gram-positive bacteria incorporate membrane-or peptidoglycan-
attached carbohydrate-based polymers into their cell envelopes. Such cell-wall …

Targeted liposomal drug delivery to monocytes and macrophages

C Kelly, C Jefferies, SA Cryan - Journal of drug delivery, 2011 - Wiley Online Library
As the role of monocytes and macrophages in a range of diseases is better understood,
strategies to target these cell types are of growing importance both scientifically and …

Innate immune gene polymorphisms in tuberculosis

AK Azad, W Sadee, LS Schlesinger - Infection and immunity, 2012 - Am Soc Microbiol
Tuberculosis (TB) is a leading cause worldwide of human mortality attributable to a single
infectious agent. Recent studies targeting candidate genes and “case-control” association …

Diversity and multiple functions of lectins in shrimp immunity

XW Wang, JX Wang - Developmental & Comparative Immunology, 2013 - Elsevier
Lectins play important roles in many biological processes, including protein trafficking, cell
signaling, pathogen recognition, as effector molecules, and so on, because of their capacity …

Prominent receptors of liver sinusoidal endothelial cells in liver homeostasis and disease

E Pandey, AS Nour, EN Harris - Frontiers in physiology, 2020 - frontiersin.org
Liver sinusoidal endothelial cells (LSECs) are the most abundant non-parenchymal cells
lining the sinusoidal capillaries of the hepatic system. LSECs are characterized with …

Fish immunity and parasite infections: from innate immunity to immunoprophylactic prospects

P Alvarez-Pellitero - Veterinary immunology and immunopathology, 2008 - Elsevier
The increasing economic importance of fish parasitoses for aquaculture and fisheries has
enhanced the interest in the defence mechanisms against these infections. Both innate and …

[HTML][HTML] C-type lectins

RD Cummings, E Chiffoleau, Y van Kooyk… - … [Internet]. 4th edition, 2022 - ncbi.nlm.nih.gov
C-type lectins (CTLs) are Ca++-dependent glycan-binding proteins (GBPs) that share
primary and secondary structural homology in their carbohydrate-recognition domains …

A review of glycosylated carriers for drug delivery

K Jain, P Kesharwani, U Gupta, NK Jain - Biomaterials, 2012 - Elsevier
Carbohydrates not only represent a vast potential as structure building blocks of living cells
but also have proved as a promising candidate for drug delivery. Glycosylation of …

The scavenger endothelial cell: a new player in homeostasis and immunity

KK Sørensen, P McCourt, T Berg… - American Journal …, 2012 - journals.physiology.org
To maintain homeostasis, the animal body is equipped with a powerful system to remove
circulating waste. This review presents evidence that the scavenger endothelial cell (SEC) is …