[HTML][HTML] Endpoints for clinical trials in ophthalmology

L Schmetterer, H Scholl, G Garhöfer… - Progress in Retinal and …, 2023 - Elsevier
With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

Vascular density of deep, intermediate and superficial vascular plexuses are differentially affected by diabetic retinopathy severity

M Ashraf, K Sampani, A Clermont… - … & Visual Science, 2020 - iovs.arvojournals.org
Purpose: The purpose of this study was to evaluate differences in optical coherence
tomography angiography (OCTA) metrics in the superficial (SCP), intermediate (ICP), and …

Wide field swept source optical coherence tomography angiography for the evaluation of proliferative diabetic retinopathy and associated lesions: a review

M Wang, I Garg, JB Miller - Seminars in ophthalmology, 2021 - Taylor & Francis
Retinal imaging remains the mainstay for monitoring and grading diabetic retinopathy. The
gold standard for detecting proliferative diabetic retinopathy (PDR) requiring treatment has …

Optical Coherence Tomography Angiography of Macular Perfusion Changes after Anti‐VEGF Therapy for Diabetic Macular Edema: A Systematic Review

AG Elnahry, GA Elnahry - Journal of Diabetes Research, 2021 - Wiley Online Library
Background. Diabetic macular edema (DME) is a major cause of vision loss in diabetics that
is currently mainly treated by antivascular endothelial growth factor (VEGF) agents. The …

Comparison of retinal layer thickness and microvasculature changes in patients with diabetic retinopathy treated with intravitreous bevacizumab vs panretinal …

MW Lee, SK Baek, KH Lee, SC Lee, JY Kim, YH Lee - Scientific reports, 2022 - nature.com
To compare changes in retinal layers and microvasculature in diabetic retinopathy (DR)
patients after bevacizumab therapy and panretinal photocoagulation (PRP). This …

Optical coherence tomography angiography in diabetes: focus on microaneurysms

G Querques, E Borrelli, M Battista, R Sacconi… - Eye, 2021 - nature.com
The introduction of optical coherence tomography angiography (OCTA) has remarkably
expanded our knowledge of the ocular vascular alterations occurring in diabetes. In this …

Astigmatism Influences Quantitative and Qualitative Analysis in Optical Coherence Tomography Angiography Imaging

L Vidal-Oliver, R Gallego-Pinazo… - … Vision Science & …, 2024 - tvst.arvojournals.org
Purpose: The purpose of this paper was to study the influence of astigmatism in optical
coherence tomography angiography (OCTA) images in a quantitative and qualitative …

Update on optical coherence tomography and optical coherence tomography angiography imaging in proliferative diabetic retinopathy

S Vaz-Pereira, T Morais-Sarmento, M Engelbert - Diagnostics, 2021 - mdpi.com
Proliferative diabetic retinopathy (PDR) is a major cause of blindness in diabetic individuals.
Optical coherence tomography (OCT) and OCT-angiography (OCTA) are noninvasive …

From diagnosis to prognosis: A paradigm shift for multimodal imaging in assessing diabetic macular edema

A Apuzzo, S Gravina, G Panozzo… - European Journal …, 2024 - journals.sagepub.com
Diabetic macular edema (DME) is one of the leading causes of visual impairment in patients
with diabetes. Multimodal imaging (MMI) has allowed a shift from DME diagnosis to …

Mean macular intercapillary area in eyes with diabetic macular oedema after anti‐vascular endothelial growth factor therapy and its association with treatment …

OA Sorour, M Elsheikh, S Chen… - Clinical & …, 2021 - Wiley Online Library
Background To evaluate the changes in the mean macular intercapillary area (ICA) from
sequential enface optical coherence tomography angiography (OCTA) images following …