Ferroptosis is a new type of oxidative regulated cell death (RCD) driven by iron-dependent
lipid peroxidation. As major sites of iron utilization and master regulators of oxidative …

Ferritin is a vital protein complex responsible for storing iron in almost all living organisms. It
plays a crucial role in various metabolic pathways, inflammation processes, stress response …

Cancer progression including proliferation, metastasis, and chemoresistance has become a
serious hindrance to cancer therapy. This phenomenon mainly derives from the innate …

Abstract Alzheimer's disease (AD), a neurodegenerative condition, is defined by
neurofibrillary tangles, amyloid plaques, and gradual cognitive decline. Regardless of the …

Systemic therapy is one of the most significant cancer treatments. However, drug resistance
often appears and has become the primary cause of cancer therapy failure. Regulation of …

Objective. Glioblastoma is one of the most common malignant tumors in the brain, and these
glioblastoma patients have very poor prognosis. Ferroptosis is involved in the progression of …

Background Metastases are the major cause of cancer-related morbidity and mortality. By
the time cancer cells detach from their primary site to eventually spread to distant sites, they …

The H Ferritin subunit (FTH1), as well as regulating the homeostasis of intracellular iron, is
involved in complex pathways that might promote or inhibit carcinogenesis. This function …

Ferroptosis is a recently discovered pattern of programmed cell death that is nonapoptotic
and irondependent. It is involved in lipid peroxidation dependent on reactive oxygen …

Olive oil contains different biologically active polyphenols, among which oleacein, the most
abundant secoiridoid, has recently emerged for its beneficial properties in various disease …