tDCS regulates ASBT-3-OxoLCA-PLOD2-PTEN signaling pathway to confer neuroprotection following rat cerebral ischemia-reperfusion injury

X Kong, X Yao, J Ren, J Gao, Y Cui, J Sun, X Xu… - Molecular …, 2023 - Springer
Humans exhibit a rich intestinal microbiome that contain high levels of bacteria capable of
producing 3-oxo-lithocholic acid (3-oxoLCA) and other secondary bile acids (BAs). The …

ATF5 attenuates the secretion of pro-inflammatory cytokines in activated microglia

J Zhu, MJ Lee, JH An, E Oh, W Chung… - International journal of …, 2023 - mdpi.com
The highly dynamic changes in microglia necessary to achieve a rapid neuroinflammatory
response require a supply of energy from mitochondrial respiration, which leads to the …

Buyang Huanwu Decoction promotes neurovascular remodeling by modulating astrocyte and microglia polarization in ischemic stroke rats

M Li, M Li, Z Lin, Y Zhuang, H Wang, J Jia, Y Lu… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Buyang Huanwu Decoction (BYHWD), one of the
most commonly utilized traditional Chinese medicine prescription for treatment of cerebral …

Itaconate alleviates anesthesia/surgery-induced cognitive impairment by activating a Nrf2-dependent anti-neuroinflammation and neurogenesis via gut-brain axis

X Kong, W Lyu, X Lin, C Lin, H Feng, L Xu… - Journal of …, 2024 - Springer
Background Postoperative cognitive dysfunction (POCD) is a common neurological
complication of anesthesia and surgery in aging individuals. Neuroinflammation has been …

Bibliometric analysis of PTEN in neurodevelopment and neurodegeneration

Y Zhang, Y Tan, M Wang, L Li, J Huang… - Frontiers in Aging …, 2024 - frontiersin.org
Phosphatase and tensin homologue deleted on chromosome ten (PTEN) was initially
recognized as a significant regulator of cancer suppression and could impede cancer cell …

Baicalin attenuates neuronal damage associated with SDH activation and PDK2-PDH axis dysfunction in early reperfusion

K Liu, Y Zhou, X Song, J Zeng, Z Wang, Z Wang… - Phytomedicine, 2024 - Elsevier
Background Energy deficiency and oxidative stress are interconnected during
ischemia/reperfusion (I/R) and serve as potential targets for the treatment of cerebral …

Cathodal bilateral transcranial direct‐current stimulation regulates selenium to confer neuroprotection after rat cerebral ischaemia–reperfusion injury

H Wang, W Ma, W Hu, X Li, N Shen, Z Li… - The Journal of …, 2024 - Wiley Online Library
Non‐invasive transcranial direct‐current stimulation (tDCS) is a safe ischaemic stroke
therapy. Cathodal bilateral tDCS (BtDCS) is a modified tDCS approach established by us …

Upregulation of mitochondrial PGK1 by ROS-TBC1D15 pathway promotes neuronal death after oxygen-glucose deprivation/reoxygenation injury

S Chen, H Wang, J Chen, J Cheng, J Gao, S Chen… - Brain Research, 2024 - Elsevier
Abstract Phosphoglycerate kinase 1 (PGK1) is extensively located in the cytosol and
mitochondria. The role of PGK1 in ischemic neuronal injury remains elusive. In the in vitro …