Anticancer potential of coumarin and its derivatives

N Bhattarai, AA Kumbhar, YR Pokharel… - Mini Reviews in …, 2021 - ingentaconnect.com
Coumarins are found in higher plants like Rutaceae and Umbelliferae and essential oils of
cinnamon bark, cassia leaf, and lavender oil. Coumarin compounds show different …

Furanocoumarins in anticancer therapy–For and against

J Sumorek-Wiadro, A Zając, A Maciejczyk… - Fitoterapia, 2020 - Elsevier
Furanocoumarins are a class of natural compounds produced by several plants, including
those consumed by humans. They have been used medicinally in eastern countries for …

Screening Antitumor Compounds Psoralen and Isopsoralen from Psoralea corylifolia L. Seeds

Y Wang, C Hong, C Zhou, D Xu… - … and Alternative Medicine, 2011 - Wiley Online Library
Psoralea corylifolia L.(Fabaceae) is a widely used medical plant in China. This study was
designed to screen and identify bioactive compounds with anticancer activity from the seeds …

6, 7-Coumarin-heterocyclic hybrids: a comprehensive review of their natural sources, synthetic approaches, and bioactivity

NM Zeki, YF Mustafa - Journal of Molecular Structure, 2024 - Elsevier
The hybridization of heterocycles presents a key opportunity to craft innovative multicyclic
compounds with enhanced biological activity. Coumarins, being broadly prevalent natural …

Visible-light-induced cyclization/aromatization of 2-vinyloxy arylalkynes: synthesis of thio-substituted dibenzofuran derivatives

H Chen, Y Yan, N Zhang, Z Mo, Y Xu, Y Chen - Organic Letters, 2020 - ACS Publications
A visible-light-induced cascade reaction of 2-vinyloxy arylalkynes with thiosulfonates was
developed and provided unexpected thio-substituted dibenzofuran derivatives in moderate …

Annulated Heterocyclic[g]Coumarin Composites: Synthetic Approaches and Bioactive Profiling

N Mazin Zeki, Y Fakri Mustafa - Chemistry & Biodiversity, 2024 - Wiley Online Library
Coumarins, widely abundant natural heterocyclic compounds, are extensively employed in
creating various biologically and pharmacologically potent substances. The hybridization of …

Mechanistic insights into the ameliorating effect of melanogenesis of psoralen derivatives in B16F10 melanoma cells

Y Lee, CG Hyun - Molecules, 2022 - mdpi.com
The objectives of this study were to investigate the melanogenetic potential of the psoralen
derivatives 5-hydroxypsoralen, 5-methoxypsoralen, 8-hydroxypsoralen, 8-methoxypsoralen …

Psoralen: a biologically important coumarin with emerging applications

A Thakur, R Sharma, VS Jaswal… - Mini reviews in …, 2020 - ingentaconnect.com
Coumarin belongs to a class of lactones that are fundamentally comprised of a benzene ring
fused to an α-pyrone ring; these lactones are known as benzopyrones. Similarly, coumarin …

Synthesis of Dibenzofurans via C–H Activation of o-Iodo Diaryl Ethers

N Panda, I Mattan, DK Nayak - The Journal of organic chemistry, 2015 - ACS Publications
An efficient method for the synthesis of dibenzofuran from o-iododiaryl ether using reusable
Pd/C under ligand-free conditions has been developed. Synthesis of o-iododiaryl ether was …

Facile assembly of fused benzo [4, 5] furo heterocycles

J Liu, AE Fitzgerald, NS Mani - The Journal of organic chemistry, 2008 - ACS Publications
A concise synthesis of fused benzo [4, 5] furo heterocycles 18 has been developed.
Chemo/regioselective Suzuki coupling between 1, 2-dihaloarene 17 and α …