A key role of the gut microbiota in the establishment and maintenance of health, as well as in
the pathogenesis of disease, has been identified over the past two decades. One of the …

Inflammatory bowel disease (IBD) is a chronic immune-mediated disease affecting the
gastrointestinal tract. IBD consists of 2 subtypes: ulcerative colitis and Crohn disease. IBD is …

For decades, variability in clinical efficacy of the widely used inflammatory bowel disease
(IBD) drug 5-aminosalicylic acid (5-ASA) has been attributed, in part, to its acetylation and …

Inflammatory bowel diseases, which include Crohn's disease and ulcerative colitis, affect
several million individuals worldwide. Crohn's disease and ulcerative colitis are complex …

Macrophages are the gatekeepers of intestinal immune homeostasis as they discriminate
between innocuous antigens and potential pathogens to maintain oral tolerance. However …

In the past period, due to the rapid development of next-generation sequencing technology,
accumulating evidence has clarified the complex role of the human microbiota in the …

B vitamins act as coenzymes in a myriad of cellular reactions. These include energy
production, methyl donor generation, neurotransmitter synthesis, and immune functions …

Background & Aims The cause of Crohn's disease (CD) is unknown, but the current
hypothesis is that microbial or environmental factors induce gut inflammation in genetically …

ABSTRACT A Western diet comprising high fat, high carbohydrate, and low fiber content has
been suggested to contribute to an increased prevalence of colitis. To clarify the effect of …

ABSTRACT A large number of microbes exist in the gut and they have the ability to process
and utilize ingested food. It has been reported that their products are involved in colorectal …