Raman spectroscopy is a potentially important clinical tool for real-time diagnosis of disease
and in situevaluation of living tissue. The purpose of this article is to review the biological …

Miniaturized flexible ultrasound catheters provide detailed information on the vessel wall.
They are an additional diagnostic evaluation technique, partly in the realm of coronary …

Background—Atherosclerotic plaque stability is related to histological composition.
However, current diagnostic tools do not allow adequate in vivo identification and …

Background Optical coherence tomography (OCT) is a recently developed medical
diagnostic technology that uses back-reflected infrared light to perform in situ micron scale …

Aims: Atherosclerosis is considered both a systemic and focal disease. Current diagnostic
tools do not allow adequate in vivo identification and characterisation of lesions. Advanced …

Objectives: The purpose of this study was to assess the prevalence of intravascular
ultrasound (IVUS)-derived thin-cap fibroatheroma (IDTCFA) and its relationship with the …

BACKGROUND: OCT can image plaque microstructure at a level of resolution not previously
demonstrated with other imaging techniques because it uses infrared light rather than …

Background—A method is needed to identify nonstenotic, lipid-rich coronary plaques that
are likely to cause acute coronary events. Near-infrared (NIR) spectroscopy can provide …

Background We studied whether lipid-lowering therapy with atorvastatin (target LDL
cholesterol [LDL-C]< 100 mg/dL) compared with a moderate treatment regimen that used …

Objectives: The purpose of the present study was to validate the diagnostic accuracy of
optical coherence tomography (OCT), integrated backscatter intravascular ultrasound (IB …