[HTML][HTML] Adaptation of high-throughput screening in drug discovery—toxicological screening tests

P Szymański, M Markowicz… - International journal of …, 2011 - mdpi.com
High-throughput screening (HTS) is one of the newest techniques used in drug design and
may be applied in biological and chemical sciences. This method, due to utilization of …

Asymmetric multicomponent reactions (AMCRs): the new frontier

DJ Ramón, M Yus - Angewandte Chemie International Edition, 2005 - Wiley Online Library
Asymmetric multicomponent reactions involve the preparation of chiral compounds by the
reaction of three or more reagents added simultaneously. This kind of addition and reaction …

Glcc: A general framework for graph-level clustering

W Ju, Y Gu, B Chen, G Sun, Y Qin, X Liu… - Proceedings of the …, 2023 - ojs.aaai.org
This paper studies the problem of graph-level clustering, which is a novel yet challenging
task. This problem is critical in a variety of real-world applications such as protein clustering …

[HTML][HTML] Multicomponent syntheses of functional chromophores

L Levi, TJJ Müller - Chemical Society Reviews, 2016 - pubs.rsc.org
Multicomponent reactions are a valuable tool for the synthesis of functional π-electron
systems. Two different approaches can be taken into account for accessing the target …

Multicomponent reactions: concepts and applications for design and synthesis

RP Herrera, E Marqués-López - 2015 - books.google.com
Addressing a dynamic aspect of organic chemistry, this book describes synthetic strategies
and applications for multicomponent reactions–including key routes for synthesizing …

DBU: a highly efficient catalyst for one-pot synthesis of substituted 3, 4-dihydropyrano [3, 2-c] chromenes, dihydropyrano [4, 3-b] pyranes, 2-amino-4H-benzo [h] …

JM Khurana, B Nand, P Saluja - Tetrahedron, 2010 - Elsevier
We have reported DBU catalyzed one-pot synthesis of 3, 4-dihydropyrano [3, 2-c]
chromenes, dihydropyrano [4, 3-b] pyranes, 2-amino-4H-benzo [h] chromenes and 2-amino …

[HTML][HTML] The chemistry of isocyanides, their multicomponent reactions and their libraries

I Ugi, B Werner, A Dömling - Molecules, 2003 - mdpi.com
The first century of isocyanide chemistry, which was then still a rather empty part of Organic
Chemistry, began in 1859. In 1958 isocyanides became generally available by dehydration …

L-Proline: an efficient catalyst for the one-pot synthesis of 2, 4, 5-trisubstituted and 1, 2, 4, 5-tetrasubstituted imidazoles

S Samai, GC Nandi, P Singh, MS Singh - Tetrahedron, 2009 - Elsevier
A simple highly versatile and efficient synthesis of 2, 4, 5-trisubstituted imidazoles is
achieved by three-component cyclocondensation of 1, 2-dicarbonyl compound, aldehyde …

Rapid four-component reactions in water: synthesis of pyranopyrazoles

G Vasuki, K Kumaravel - Tetrahedron Letters, 2008 - Elsevier
Rapid four-component reactions in water: synthesis of pyranopyrazoles - ScienceDirect
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Multiple multicomponent macrocyclizations (MiBs): a strategic development toward macrocycle diversity

LA Wessjohann, DG Rivera, OE Vercillo - Chemical reviews, 2009 - ACS Publications
Macrocycles are of high significance in areas as diverse as drug development and
supramolecular chemistry. They can be considered as privileged molecules because they …