Much of our knowledge on K+-channels was elucidated using specific peptide ligands
isolated from a number of venomous organisms. Recently, this field received a strong …

Animal toxins acting on ion channels of excitable cells are principally highly potent short
peptides that are present in limited amounts in the venoms of various unrelated species …

Animal venoms are rich natural sources of bioactive compounds, including peptide toxins
acting on the various types of ion channels, ie K+, Na+, Cl-and Ca2+. Among K+ channel …

Potassium (K+) channels are a widespread superfamily of integral membrane proteins that
mediate selective transport of K+ ions through the cell membrane. They have been found in …

Recent discoveries suggest cysteine-stabilized toxins and antimicrobial peptides have
structure–activity parallels derived by common ancestry. Here, human antimicrobial peptide …

Venom and poison peptides are powerful biological weapons and have proven immense
pharmacological potential because of their high binding affinity to a wide range of molecular …

OSK1 (α-KTx3. 7) is a 38-residue toxin cross-linked by three disulphide bridges that was
initially isolated from the venom of the Asian scorpion Orthochirus scrobiculosus. OSK1 and …

During the last two decades since the identification and characterization of T cell potassium
channels great advances have been made in the understanding of the role of these …

A cDNA encoding gallerimycin, a novel antifungal peptide from the greater wax moth
Galleria mellonella, was isolated from a cDNA library of genes expressed during innate …

Scorpion K+ channel toxins and insect defensins share a conserved three-dimensional
structure and related biological activities (defense against competitors or invasive microbes …