Using guinea pigs in studies relevant to asthma and COPD
BJ Canning, Y Chou - Pulmonary pharmacology & therapeutics, 2008 - Elsevier
The guinea pig has been the most commonly used small animal species in preclinical
studies related to asthma and COPD. The primary advantages of the guinea pig are the …
studies related to asthma and COPD. The primary advantages of the guinea pig are the …
Tissue Inhibitor of Metalloproteinases-2 (TIMP-2) as a Prognostic Biomarker in Acute Kidney Injury: A Narrative Review
C Delrue, MM Speeckaert - Diagnostics, 2024 - mdpi.com
Acute kidney damage (AKI) is a serious and common consequence among critically unwell
individuals. Traditional biomarkers, such as serum creatinine, frequently fail to detect AKI in …
individuals. Traditional biomarkers, such as serum creatinine, frequently fail to detect AKI in …
Hyperoxia decreases matrix metalloproteinase-9 and increases tissue inhibitor of matrix metalloproteinase-1 protein in the newborn rat lung: association with arrested …
GE Hosford, XIN Fang, DM Olson - Pediatric research, 2004 - nature.com
Matrix metalloproteinases (MMP) are likely effectors of normal lung development, especially
branching morphogenesis, angiogenesis, and extracellular matrix degradation. Because …
branching morphogenesis, angiogenesis, and extracellular matrix degradation. Because …
The role of NLRP3 inflammasome-mediated pyroptosis in astrocytes during hyperoxia-induced brain injury
Q Liu, Y Tan, ZW Zhang, W Tang, L Han, KP Peng… - Inflammation …, 2025 - Springer
Background Hyperoxia-induced brain injury is a severe neurological complication that is
often accompanied by adverse long-term prognosis. The pathogenesis of hyperoxia …
often accompanied by adverse long-term prognosis. The pathogenesis of hyperoxia …
Tissue inhibitor of metalloproteinases-4 is expressed in cervical cancer patients
Background: Tissue Inhibitors of Metalloproteinases (TIMPs) play a critical role in
extracellular matrix remodeling, which is involved in tumor growth and metastasis. Elevated …
extracellular matrix remodeling, which is involved in tumor growth and metastasis. Elevated …
[PDF][PDF] 基质金属蛋白酶一2 及其抑制物一2 在高氧致慢性肺疾病新生大鼠肺组织中的动态变化及意义
刘雪雁， 薛辛东 - 中国危重病急救医学, 2008 - cccm-em120.com
目的探讨基质金属蛋白酶一2 (MMP 一2) 及其抑制物一2 (TIMP 一2) mRNA
和蛋白在高氧致慢性肺疾病(CLD) 新生大鼠肺组织中的动态表达规律以及在CLD …
和蛋白在高氧致慢性肺疾病(CLD) 新生大鼠肺组织中的动态表达规律以及在CLD …
猪TIMP-2 基因克隆, 序列特征和表达分析
黄宏刚， 肖邦， 任红艳， 唐中林， 杨述林， 崔文涛… - 畜牧兽医学报, 2009 - xmsyxb.com
本研究分析了五指山试验用小型猪TIMP 2 基因的分子特性和可能的生物学功能. 将人TIMP 2
mRNA 全长序列在猪ESTs 数据库中检索获得同源性较高的ESTs, 用电子克隆结合RT PCR …
mRNA 全长序列在猪ESTs 数据库中检索获得同源性较高的ESTs, 用电子克隆结合RT PCR …