An introduction to psychedelic neuroscience

T Calvey, FM Howells - Progress in brain research, 2018 - Elsevier
This chapter is an introduction to the volume “Psychedelic Neuroscience” of Elsevier's
Progress in Brain Research addressing the neurobiological mechanisms of psychedelic …

Antipsychotics-induced changes in synaptic architecture and functional connectivity: translational implications for treatment response and resistance

A de Bartolomeis, G De Simone, M Ciccarelli… - Biomedicines, 2022 - mdpi.com
Schizophrenia is a severe mental illness characterized by alterations in processes that
regulate both synaptic plasticity and functional connectivity between brain regions …

Functional networks and network perturbations in rodents

KH Chuang, FA Nasrallah - Neuroimage, 2017 - Elsevier
Synchronous low-frequency oscillation in the resting human brain has been found to form
networks of functionally associated areas and hence has been widely used to map the …

A fluorescent sensor based on thioglycolic acid capped cadmium sulfide quantum dots for the determination of dopamine

S Kulchat, W Boonta, A Todee, P Sianglam… - … Acta Part A: Molecular …, 2018 - Elsevier
A fluorescent sensor based on thioglycolic acid-capped cadmium sulfide quantum dots (TGA-
CdS QDs) has been designed for the sensitive and selective detection of dopamine (DA). In …

[HTML][HTML] Simultaneous fMRI and fast-scan cyclic voltammetry bridges evoked oxygen and neurotransmitter dynamics across spatiotemporal scales

LR Walton, M Verber, SH Lee, THH Chao… - Neuroimage, 2021 - Elsevier
The vascular contributions of neurotransmitters to the hemodynamic response are gaining
more attention in neuroimaging studies, as many neurotransmitters are vasomodulatory. To …

P2X7 receptor-dependent layer-specific changes in neuron-microglia reactivity in the prefrontal cortex of a phencyclidine induced mouse model of schizophrenia

S Calovi, P Mut-Arbona, P Tod, A Iring… - Frontiers in molecular …, 2020 - frontiersin.org
Background: It has been consistently reported that the deficiency of the adenosine
triphosphate (ATP) sensitive purinergic receptor P2X7 (P2X7R) ameliorates symptoms in …

Frontostriatal functional connectivity and striatal dopamine synthesis capacity in schizophrenia in terms of antipsychotic responsiveness: an [18F] DOPA PET and fMRI …

S Kim, WH Jung, OD Howes, M Veronese… - Psychological …, 2019 - cambridge.org
BackgroundGiven that only a subgroup of patients with schizophrenia responds to first-line
antipsychotic drugs, a key clinical question is what underlies treatment response …

The effects of donepezil on phencyclidine-induced cognitive deficits in a mouse model of schizophrenia

YX Li, ZH Ye, T Chen, XF Jia, L He - Pharmacology Biochemistry and …, 2018 - Elsevier
Donepezil is the first-line of treatment for Alzheimer's disease (AD), which improves
cognitive impairment effectively, but whether it has an impact on cognitive impairment in …

Temporal dissociation of phencyclidine: Induced locomotor and social alterations in rats using an automated homecage monitoring system–implications for the 3Rs …

EJ Mitchell, RR Brett, JD Armstrong… - Journal of …, 2020 - journals.sagepub.com
Background: Rodent behavioural assays are widely used to delineate the mechanisms of
psychiatric disorders and predict the efficacy of drug candidates. Conventional behavioural …

Selective adrenergic alpha2C receptor antagonist ameliorates acute phencyclidine-induced schizophrenia-like social interaction deficits in rats

K Savolainen, J Ihalainen, AJ Jalkanen… - …, 2019 - Springer
Rationale Social withdrawal is a core feature of the negative symptoms of schizophrenia.
Currently available pharmacotherapies have only limited efficacy towards the negative …