[HTML][HTML] Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer

W Fong, Q Li, J Yu - Oncogene, 2020 - nature.com
Research about the role of gut microbiome in colorectal cancer (CRC) is a newly emerging
field of study. Gut microbiota modulation, with the aim to reverse established microbial …

[HTML][HTML] Mouse microbiota models: comparing germ-free mice and antibiotics treatment as tools for modifying gut bacteria

EA Kennedy, KY King, MT Baldridge - Frontiers in physiology, 2018 - frontiersin.org
As the intestinal microbiota has become better appreciated as necessary for maintenance of
physiologic homeostasis and also as a modulator of disease processes, there has been a …

[HTML][HTML] Wild mouse gut microbiota promotes host fitness and improves disease resistance

SP Rosshart, BG Vassallo, D Angeletti, DS Hutchinson… - Cell, 2017 - cell.com
Laboratory mice, while paramount for understanding basic biological phenomena, are
limited in modeling complex diseases of humans and other free-living mammals. Because …

The role of the gut microbiome in colorectal cancer development and therapy response

L Sánchez-Alcoholado, B Ramos-Molina, A Otero… - Cancers, 2020 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer worldwide and the leading cause
of cancer-related deaths. Recently, several studies have demonstrated that gut microbiota …

The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation

A Langdon, N Crook, G Dantas - Genome medicine, 2016 - Springer
The widespread use of antibiotics in the past 80 years has saved millions of human lives,
facilitated technological progress and killed incalculable numbers of microbes, both …

Human gut microbiota and gastrointestinal cancer

C Meng, C Bai, TD Brown, LE Hood… - Genomics, Proteomics …, 2018 - academic.oup.com
Human gut microbiota play an essential role in both healthy and diseased states of humans.
In the past decade, the interactions between microorganisms and tumors have attracted …

Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells

C Burrello, F Garavaglia, FM Cribiù, G Ercoli… - Nature …, 2018 - nature.com
Alteration of the gut microbiota has been associated with different gastrointestinal disorders.
Normobiosis restoration by faecal microbiota transplantation (FMT) is considered a …

[HTML][HTML] De novo clustering methods outperform reference-based methods for assigning 16S rRNA gene sequences to operational taxonomic units

SL Westcott, PD Schloss - PeerJ, 2015 - peerj.com
Background. 16S rRNA gene sequences are routinely assigned to operational taxonomic
units (OTUs) that are then used to analyze complex microbial communities. A number of …

Gut microbiota in colorectal cancer: biological role and therapeutic opportunities

H Pandey, DWT Tang, SH Wong, D Lal - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the second-leading cause of cancer-related
deaths worldwide. In this review article, we examine the role of gut microbiota in the …

Microbiota and reproducibility of rodent models

CL Franklin, AC Ericsson - Lab animal, 2017 - nature.com
The gut microbiota (GM) plays a critical role in human health and disease. Likewise, it is
becoming increasingly evident that changes or disruptions to the GM can have significant …