The role of inhibitory circuits in hippocampal memory processing

L Topolnik, S Tamboli - Nature Reviews Neuroscience, 2022 - nature.com
GABAergic inhibitory circuits play an essential role in coordinating various hippocampal
functions. Several decades of work dedicated to a thorough characterization of hippocampal …

The role of the hippocampus in the consolidation of emotional memories during sleep

É Pronier, JF Morici, G Girardeau - Trends in Neurosciences, 2023 - cell.com
Episodic memory relies on the hippocampus, a heterogeneous brain region with distinct
functions. Spatial representations in the dorsal hippocampus (dHPC) are crucial for …

110 μm thin endo-microscope for deep-brain in vivo observations of neuronal connectivity, activity and blood flow dynamics

M Stibůrek, P Ondráčková, T Tučková, S Turtaev… - Nature …, 2023 - nature.com
Light-based in-vivo brain imaging relies on light transport over large distances of highly
scattering tissues. Scattering gradually reduces imaging contrast and resolution, making it …

Cortical regulation of two-stage rapid eye movement sleep

Y Dong, J Li, M Zhou, Y Du, D Liu - Nature neuroscience, 2022 - nature.com
Rapid eye movement (REM) sleep is a sleep state characterized by skeletal muscle
paralysis and cerebral cortical activation. Yet, global cortical dynamics and their role in …

Functionally distinct high and low theta oscillations in the human hippocampus

A Goyal, J Miller, SE Qasim, AJ Watrous… - Nature …, 2020 - nature.com
Based on rodent models, researchers have theorized that the hippocampus supports
episodic memory and navigation via the theta oscillation, a~ 4–10 Hz rhythm that …

Lateral septum as a nexus for mood, motivation, and movement

HS Wirtshafter, MA Wilson - Neuroscience & biobehavioral reviews, 2021 - Elsevier
The lateral septum (LS) has been implicated in a wide variety of functions, including
emotional, motivational, and spatial behavior, and the LS may regulate interactions between …

The relationships between stress, mental disorders, and epigenetic regulation of BDNF

Z Miao, Y Wang, Z Sun - International journal of molecular sciences, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF), a critical member of the neurotrophic family, plays
an important role in multiple stress-related mental disorders. Although alterations in BDNF in …

The medial septum controls hippocampal supra-theta oscillations

B Király, A Domonkos, M Jelitai… - nature …, 2023 - nature.com
Hippocampal theta oscillations orchestrate faster beta-to-gamma oscillations facilitating the
segmentation of neural representations during navigation and episodic memory. Supra …

Cortical disinhibitory circuits: cell types, connectivity and function

K Kullander, L Topolnik - Trends in Neurosciences, 2021 - cell.com
The concept of a dynamic excitation/inhibition balance tuned by circuit disinhibition, which
can shape information flow during complex behavioral tasks, has arisen as an important and …

Thalamic nucleus reuniens coordinates prefrontal-hippocampal synchrony to suppress extinguished fear

MS Totty, T Tuna, KR Ramanathan, J Jin… - Nature …, 2023 - nature.com
Traumatic events result in vivid and enduring fear memories. Suppressing the retrieval of
these memories is central to behavioral therapies for pathological fear. The medial prefrontal …