The PPARα and PPARγ epigenetic landscape in cancer and immune and metabolic disorders

J Porcuna, J Mínguez-Martínez, M Ricote - International journal of …, 2021 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) are ligand-modulated nuclear
receptors that play pivotal roles in nutrient sensing, metabolism, and lipid-related processes …

PPARs in Clinical Experimental Medicine after 35 Years of Worldwide Scientific Investigations and Medical Experiments

A Skoczyńska, M Ołdakowska, A Dobosz, R Adamiec… - Biomolecules, 2024 - mdpi.com
This year marks the 35th anniversary of Professor Walter Wahli's discovery of the PPARs
(Peroxisome Proliferator-Activated Receptors) family of nuclear hormone receptors. To mark …

Ferroptosis-related gene signature predicts the prognosis of papillary thyroid carcinoma

J Shi, P Wu, L Sheng, W Sun, H Zhang - Cancer Cell International, 2021 - Springer
Background Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer
(TC), accounting for more than 80% of all cases. Ferroptosis is a novel iron-dependent and …

Assessment of causal association between differentiated thyroid cancer and disordered serum lipid profile: a Mendelian randomization study

Q Ma, Y Li, L An, L Guo, X Liu - Frontiers in Endocrinology, 2023 - frontiersin.org
Background Research has shown that the disordered serum lipid profile may be associated
with the risk of differentiated thyroid cancer (DTC). Whether this association reflect causal …

Chromatin-accessible miRNA regulons driving thyroid tumorigenesis and progression

EA Toraih, E Ruiz, B Ning, GG Tortelote… - Journal of the …, 2023 - journals.lww.com
BACKGROUND: Although papillary thyroid cancer can remain indolent, associated lymph
node metastases and recurrence rates are approximately 50% and 20%, respectively …

Changes in Liver Function and Lipid Profile during Underactive Thyroid Phase in Patients after Subtotal Thyroidectomy: Changes in Liver Function and Lipid Profile …

Z Haq, SUS Zaidi, M Umar, MS Ali… - Pakistan Journal of …, 2024 - mail.thejas.com.pk
Abstract Underactive Thyroid Phase or Hypothyroidism is a very common biochemical
complication after sub-total thyroidectomy. Objectives: To investigate lipid profile and liver …