An overview of novel antimicrobial carbonic anhydrase inhibitors

CT Supuran - Expert Opinion on Therapeutic Targets, 2023 - Taylor & Francis
Introduction Four different genetic families of the enzyme carbonic anhydrase (CA, EC 4.2.
1.1) are present in bacteria, α-, β-, γ-and ι-CAs. They play relevant functions related to CO2 …

[HTML][HTML] The role of vaccines in combating antimicrobial resistance (AMR) bacteria

S Alghamdi - Saudi Journal of Biological Sciences, 2021 - Elsevier
Most pathogens have developed an intrinsic capacity to thrive by developing resistance to
antimicrobial compounds utilized in treatment. Antimicrobial resistance arises when …

Dissemination and genome analysis of high-level ceftriaxone-resistant penA 60.001 Neisseria gonorrhoeae strains from the Guangdong Gonococcal antibiotics …

X Lin, W Chen, Q Xie, Y Yu, Y Liao, Z Feng… - Emerging Microbes & …, 2022 - Taylor & Francis
ABSTRACT Background: After Neisseria gonorrhoeae FC428 was first found in Japan,
ceftriaxone-resistant strains disseminated globally, and the gonococcal resistance rate …

Characterization and antioxidant activity of nano-formulated berberine and cyperus rotundus extracts with anti-inflammatory effects in mastitis-induced rats

AE Hashem, IH Elmasry, MA Lebda, DRSG El-Karim… - Scientific Reports, 2024 - nature.com
Bovine mastitis caused by infectious pathogens, mainly Staphylococcus aureus (S. aureus)
and Escherichia coli (E. coli), constitutes a major destructive challenge for the dairy industry …

Computer-aided genomic data analysis of drug-resistant Neisseria gonorrhoeae for the Identification of alternative therapeutic targets

A Qasim, S Jaan, TU Wara, M Shehroz… - Frontiers in Cellular …, 2023 - frontiersin.org
Neisseria gonorrhoeae is an emerging multidrug resistance pathogen that causes sexually
transmitted infections in men and women. The N. gonorrhoeae has demonstrated an …

Chlamydial and Gonococcal Genital Infections: A Narrative Review

R Rodrigues, P Vieira-Baptista, C Catalão… - Journal of Personalized …, 2023 - mdpi.com
Sexually transmitted infections (STIs) constitute one of the leading causes of disease burden
worldwide, leading to considerable morbidity, mortality, health expenditures, and stigma. Of …

Development and application of Cas13a-based diagnostic assay for Neisseria gonorrhoeae detection and azithromycin resistance identification

H Luo, W Chen, Z Mai, J Yang, X Lin… - Journal of …, 2022 - academic.oup.com
Abstract Background Gonorrhoea, caused by Neisseria gonorrhoeae, has spread
worldwide. Strains resistant to most antibiotics, including ceftriaxone and azithromycin, have …

Novel strain of multidrug non-susceptible Neisseria gonorrhoeae in the USA

JL Reimche, CD Pham, SJ Joseph, S Hutton… - The Lancet Infectious …, 2024 - thelancet.com
Unsuccessful treatment of gonor rhoea has not yet occurred in the USA, and cases of
gonorrhoea that are non susceptible to cephalosporins have been rare. In 2019 …

Structural and Functional Annotation and Molecular Docking Analysis of a Hypothetical Protein from Neisseria gonorrhoeae: An In‐Silico Approach

L Mazumder, MR Hasan, K Fatema… - BioMed Research …, 2022 - Wiley Online Library
Background. Worldwide, Neisseria gonorrhoeae‐related sexually transmitted infections
(STIs) continue to be of significant public health concern. This obligate‐human pathogen …

Genomic epidemiology of Neisseria gonorrhoeae in Shenzhen, China, during 2019–2020: increased spread of ceftriaxone-resistant isolates brings insights for …

D Wang, Y Li, C Zhang, Y Zeng, J Peng… - Microbiology …, 2023 - Am Soc Microbiol
The antimicrobial resistance (AMR) in gonorrhea poses global threat of increasing public
health concern. In response to this concern, molecular surveillance has been widely utilized …