Collagen hydrogels are among​ the most well-studied platforms for drug delivery and in situ
tissue engineering, thanks to their low cost, low immunogenicity, versatility, biocompatibility …

Hydrogels are one of the most commonly explored classes of biomaterials. Their chemical
and structural versatility has enabled their use across a wide range of applications, including …

The lysyl oxidase family comprises five members in mammals, lysyl oxidase (LOX) and four
lysyl oxidase like proteins (LOXL1-4). They are copper amine oxidases with a highly …

Bleeding caused by trauma or surgery is a serious health problem, and uncontrollable
bleeding can result in death. Therefore, developing safe, effective, and convenient …

The dermal extracellular matrix (ECM) comprises the bulk of skin and confers strength and
resiliency. In young skin, fibroblasts produce and adhere to the dermal ECM, which is …

Fibrosis in adipose tissue is a major driver of obesity-related metabolic dysregulation. It is
characterized by an overaccumulation of extracellular matrix (ECM) during unhealthy …

A tendon transfers force from the contracting muscle to the skeletal system to produce
movement and is therefore a crucial component of the entire muscle‐tendon complex and its …

The basic building block of the extra-cellular matrix in native tissue is collagen. As a
structural protein, collagen has an inherent biocompatibility making it an ideal material for …

Fibrillar collagens (types I, II, III, V, XI, XXIV and XXVII) constitute a sub-group within the
collagen family (of which there are 28 types in humans) whose functions are to provide three …

In addition to providing a macromolecular scaffold, the extracellular matrix (ECM) is a critical
regulator of cell function by virtue of specific physical, biochemical, and mechanical …