Understanding the impact of antibiotic perturbation on the human microbiome

DJ Schwartz, AE Langdon, G Dantas - Genome medicine, 2020 - Springer
The human gut microbiome is a dynamic collection of bacteria, archaea, fungi, and viruses
that performs essential functions for immune development, pathogen colonization …

The biological activities of postbiotics in gastrointestinal disorders

A Abbasi, AH Rad, Z Ghasempour… - Critical Reviews in …, 2022 - Taylor & Francis
According to outcomes from clinical studies, an intricate relationship occurs between the
beneficial microbiota, gut homeostasis, and the host's health status. Numerous studies have …

[HTML][HTML] High-fat diet promotes colitis-associated tumorigenesis by altering gut microbial butyrate metabolism

X Shao, L Liu, Y Zhou, K Zhong, J Gu, T Hu… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Background: Dietary fat intake is associated with an increased risk of colitis associated
cancer (CAC). A high-fat diet (HFD) leads to systemic low-grade inflammation. The colon is …

Combination strategies to augment immune check point inhibitors efficacy-implications for translational research

H Varayathu, V Sarathy, BE Thomas, SS Mufti… - Frontiers in …, 2021 - frontiersin.org
Immune checkpoint inhibitor therapy has revolutionized the field of cancer immunotherapy.
Even though it has shown a durable response in some solid tumors, several patients do not …

Current methodologies to refine bioavailability, delivery, and therapeutic efficacy of plant flavonoids in cancer treatment

CG Vazhappilly, M Amararathna, AC Cyril… - The Journal of …, 2021 - Elsevier
Over the last two decades, several advancements have been made to improve the
therapeutic efficacy of plant flavonoids, especially in cancer treatment. Factors such as low …

[HTML][HTML] Postbiotics as promising tools for cancer adjuvant therapy

AH Rad, LA Maleki, HS Kafil, HF Zavoshti… - Advanced …, 2021 - ncbi.nlm.nih.gov
As many investigations have reported, there is a complicated relation between fermented
foods, lactic acid bacteria (LAB), and human health. It seems that bioactive components …

[HTML][HTML] Investiture of next generation probiotics on amelioration of diseases–Strains do matter

TL Lin, CC Shu, WF Lai, CM Tzeng, HC Lai… - Medicine in …, 2019 - Elsevier
The roles of newly identified, non-conventional, native gut microbiota bacteria for promotion
of health and even therapeutic purposes have rapidly attracted much more attention in …

The interaction between intratumoral microbiome and immunity is related to the prognosis of ovarian cancer

D Sheng, K Yue, H Li, L Zhao, G Zhao, C Jin… - Microbiology …, 2023 - Am Soc Microbiol
Microbiota can influence the occurrence, development, and therapeutic response of a wide
variety of cancer types by modulating immune responses to tumors. Recent studies have …

The gut microbiota: a potential gateway to improved health outcomes in breast cancer treatment and survivorship

K Sampsell, D Hao, RA Reimer - International Journal of Molecular …, 2020 - mdpi.com
Breast cancer is the most frequently diagnosed cancer in women worldwide. The disease
and its treatments exert profound effects on an individual's physical and mental health …

JK5G postbiotics attenuate immune-related adverse events in NSCLC patients by regulating gut microbiota: a randomized controlled trial in China

M Chen, L Ma, H Yu, S Huang, J Zhang, J Gong… - Frontiers in …, 2023 - frontiersin.org
Scope This study aimed to evaluate the effects of JK5G postbiotics to regulate imbalanced
gut microbiota and its impacts on the efficacy and incidence rate of immune-related adverse …