Cardiovascular risk reduction in high-risk pediatric patients: a scientific statement from the American Heart Association

SD De Ferranti, J Steinberger, R Ameduri, A Baker… - Circulation, 2019 - Am Heart Assoc
This scientific statement presents considerations for clinical management regarding the
assessment and risk reduction of select pediatric populations at high risk for premature …

Review of childhood obesity: from epidemiology, etiology, and comorbidities to clinical assessment and treatment

S Kumar, AS Kelly - Mayo Clinic Proceedings, 2017 - Elsevier
Childhood obesity has emerged as an important public health problem in the United States
and other countries in the world. Currently 1 in 3 children in the United States is afflicted with …

Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota

CJ Chang, CS Lin, CC Lu, J Martel, YF Ko… - Nature …, 2015 - nature.com
Obesity is associated with low-grade chronic inflammation and intestinal dysbiosis.
Ganoderma lucidum is a medicinal mushroom used in traditional Chinese medicine with …

The metabolic syndrome in children and adolescents: shifting the focus to cardiometabolic risk factor clustering

SN Magge, E Goodman, SC Armstrong, S Daniels… - …, 2017 - publications.aap.org
Dr Magge served as the lead author and organized the writing and revising efforts of the
team, conceptualized and drafted the initial manuscript, and critically reviewed the revised …

Severe obesity in children and adolescents: identification, associated health risks, and treatment approaches: a scientific statement from the American Heart …

AS Kelly, SE Barlow, G Rao, TH Inge, LL Hayman… - Circulation, 2013 - Am Heart Assoc
Severe obesity afflicts between 4% and 6% of all youth in the United States, and the
prevalence is increasing. Despite the serious immediate and long-term cardiovascular …

Metformin and cancer risk and mortality: a systematic review and meta-analysis taking into account biases and confounders

S Gandini, M Puntoni, BM Heckman-Stoddard… - Cancer prevention …, 2014 - AACR
Previous meta-analyses have shown that the antidiabetic agent metformin is associated with
reduced cancer incidence and mortality. However, this effect has not been consistently …

Metformin: an old but still the best treatment for type 2 diabetes

LBA Rojas, MB Gomes - Diabetology & metabolic syndrome, 2013 - Springer
The management of T2DM requires aggressive treatment to achieve glycemic and
cardiovascular risk factor goals. In this setting, metformin, an old and widely accepted first …

Metformin and cancer risk in diabetic patients: a systematic review and meta-analysis

A DeCensi, M Puntoni, P Goodwin, M Cazzaniga… - Cancer prevention …, 2010 - AACR
Metformin, an insulin-lowering agent, has been associated with decreased cancer risk in
epidemiologic studies in diabetic patients. We performed a comprehensive literature search …

Childhood obesity

R Lakshman, CE Elks, KK Ong - Circulation, 2012 - Am Heart Assoc
Childhood obesity has important consequences for health and wellbeing both during
childhood and also in later adult life. The rising prevalence of childhood obesity poses a …

[HTML][HTML] Correcting vitamin D insufficiency improves insulin sensitivity in obese adolescents: a randomized controlled trial

AM Belenchia, AK Tosh, LS Hillman… - The American journal of …, 2013 - Elsevier
Background: Obese adolescents are at a greater risk of vitamin D deficiency because
vitamin D is thought to be sequestered by excess adipose tissue. Poor vitamin D status has …