Molecular photoswitches in aqueous environments

J Volarić, W Szymanski, NA Simeth… - Chemical Society …, 2021 - pubs.rsc.org
Molecular photoswitches enable dynamic control of processes with high spatiotemporal
precision, using light as external stimulus, and hence are ideal tools for different research …

Visible and near-infrared light activated azo dyes

H Chen, W Chen, Y Lin, Y Xie, SH Liu, J Yin - Chinese Chemical Letters, 2021 - Elsevier
The photoisomerization properties of azo derivatives have been widely used in the fields of
materials and biology. One serious restriction to the development of functional azo-based …

Azobispyrazole family as photoswitches combining (near‐) quantitative bidirectional isomerization and widely tunable thermal half‐lives from hours to years

Y He, Z Shangguan, ZY Zhang, M Xie… - Angewandte Chemie …, 2021 - Wiley Online Library
Azobenzenes are classical molecular photoswitches that have been widely used. In recent
endeavors of molecular design, replacing one or both phenyl rings with heteroaromatic rings …

Thiazolylazopyrazoles as Nonsymmetric Bis‐Heteroaryl Azo Switches: High‐Yield Visible‐Light Photoisomerization and Increased Z‐Isomer Stability by o …

T Dang, D Dong, J Zhang, Y He… - Angewandte Chemie …, 2023 - Wiley Online Library
Following the progress on mono‐heteroaryl azo switches (Het‐N= N‐Ph), a few bis‐
heteroaryl azo switches (Het‐N= N‐Het) have been studied recently, whereas the …

(Hetero) arylazo-1, 2, 3-triazoles:“Clicked” photoswitches for versatile functionalization and electronic decoupling

D Fang, ZY Zhang, Z Shangguan, Y He… - Journal of the …, 2021 - ACS Publications
The development of light-responsive chemical systems often relies on the rational design
and suitable incorporation of molecular photoswitches such as azobenzenes. Linking a …

Photoswitchable azo-and diazocine-functionalized derivatives of the VEGFR-2 inhibitor axitinib

L Heintze, D Schmidt, T Rodat, L Witt, J Ewert… - International journal of …, 2020 - mdpi.com
In this study, we aimed at the application of the concept of photopharmacology to the
approved vascular endothelial growth factor receptor (VEGFR)-2 kinase inhibitor axitinib. In …

Molecular azo–imidazole photoswitches: Property tuning by substitution

V Jelínková, A Dellai, M Vachtlová, M Fecková… - … of Photochemistry and …, 2024 - Elsevier
Azo–imidazole photoswitches based on NH–and N–methylimidazole were designed and
prepared via a convenient synthetic route. These azo-compounds were investigated by …

Synthesis of imidazole-pyrazole conjugates bearing aryl spacer and exploring their enzyme inhibition potentials

F Chaudhry, W Shahid, M Al-Rashida, M Ashraf… - Bioorganic …, 2021 - Elsevier
Developing improved enzyme inhibitors is an effective therapy to counter various diseases.
Aiming to build up biologically active templates, a new series of bis-diazoles conjugated with …

Trifluoromethyl-substituted aryldiazenyl-pyrazolo [1, 5-a] pyrimidin-2-amines: Regioselective synthesis, structure, and optical properties

FS Stefanello, YG Kappenberg, JN Araujo… - Journal of Fluorine …, 2022 - Elsevier
This paper describes for the first time an efficient approach to synthesize a novel
trifluoromethylated heterocyclic system of seventeen examples of substituted …

Data-driven discovery of molecular photoswitches with multioutput Gaussian processes

RR Griffiths, JL Greenfield, AR Thawani… - Chemical …, 2022 - pubs.rsc.org
Photoswitchable molecules display two or more isomeric forms that may be accessed using
light. Separating the electronic absorption bands of these isomers is key to selectively …