[HTML][HTML] Pharmacological basis and new insights of taxifolin: A comprehensive review

A Das, R Baidya, T Chakraborty, AK Samanta… - Biomedicine & …, 2021 - Elsevier
The pharmacological characteristics of phytochemicals have prompted a lot of interest in
their application in disease management. Due to the high incidence of cancer related …

The hallmarks of flavonoids in cancer

LGS Ponte, ICB Pavan, MCS Mancini, LGS da Silva… - Molecules, 2021 - mdpi.com
Flavonoids represent an important group of bioactive compounds derived from plant-based
foods and beverages with known biological activity in cells. From the modulation of …

Flavonoids: structure–function and mechanisms of action and opportunities for drug development

S Safe, A Jayaraman, RS Chapkin, M Howard… - Toxicological …, 2021 - Springer
Flavonoids are polyphenolic phytochemicals produced in fruits, nuts and vegetables and
dietary consumption of these structurally diverse compounds is associated with multiple …

Targeting cancer with phytochemicals via their fine tuning of the cell survival signaling pathways

S Chirumbolo, G Bjørklund, R Lysiuk, A Vella… - International journal of …, 2018 - mdpi.com
The role of phytochemicals as potential prodrugs or therapeutic substances against tumors
has come in the spotlight in the very recent years, thanks to the huge mass of encouraging …

Cholesterol-lowering phytochemicals: Targeting the mevalonate pathway for anticancer interventions

K Laka, L Makgoo, Z Mbita - Frontiers in Genetics, 2022 - frontiersin.org
There are a plethora of cancer causes and the road to fully understanding the
carcinogenesis process remains a dream that keeps changing. However, a list of role …

[HTML][HTML] Flavonoids as promising molecules in the cancer therapy: An insight

SA Mir, A Dar, L Hamid, N Nisar, JA Malik, T Ali… - Current Research in …, 2023 - Elsevier
Cancer continues to increase global morbidity and mortality rates. Despite substantial
progress in the development of various chemically synthesized anti-cancer drugs, the poor …

Quercetin loaded folate targeted plasmonic silver nanoparticles for light activated chemo-photothermal therapy of DMBA induced breast cancer in Sprague Dawley …

P Bose, A Priyam, R Kar, SP Pattanayak - RSC advances, 2020 - pubs.rsc.org
Currently, the paucity of free drugs in conventional chemotherapy for breast-cancer curbs
the desired therapeutic efficiency, often aggravating systemic toxicity. Quercetin (QRC) is a …

[HTML][HTML] New perspectives of taxifolin in neurodegenerative diseases

R Yang, X Yang, F Zhang - Current Neuropharmacology, 2023 - ncbi.nlm.nih.gov
Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD),
cerebral amyloid angiopathy (CAA), and Huntington's disease (HD) are characterized by …

LC-MS characterized methanolic extract of zanthoxylum armatum possess anti-breast cancer activity through Nrf2-Keap1 pathway: An in-silico, in-vitro and in-vivo …

R Sahu, RK Kar, P Sunita, P Bose, P Kumari… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Zanthoxylum armatum DC (Rutaceae) containing
flavonoids, alkaloids, coumarins, lignans, amides and terpenoid is well-known for its curative …

Maf1 regulates dendritic morphogenesis and influences learning and memory

K Chen, L Zhu, L Guo, YB Pan, DF Feng - Cell death & disease, 2020 - nature.com
Maf1, a general transcriptional regulator and mTOR downstream effector, is highly
expressed in the hippocampus and cortex, but the function of Maf1 in neurons is not well …