The use of RNA-based treatments in the field of cancer immunotherapy

M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

Antimicrobial and immunomodulatory properties and applications of marine-derived proteins and peptides

HK Kang, HH Lee, CH Seo, Y Park - Marine Drugs, 2019 - mdpi.com
Marine organisms provide an abundant source of potential medicines. Many of the marine-
derived biomaterials have been shown to act as different mechanisms in immune …

Head and neck squamous cell carcinoma: risk factors, molecular alterations, immunology and peptide vaccines

Z Sun, X Sun, Z Chen, J Du, Y Wu - International Journal of Peptide …, 2022 - Springer
Head and neck squamous cell carcinoma (HNSCC) arises from the epithelial lining of the
oral cavity, hypopharynx, oropharynx, and larynx. There are several potential risk factors that …

Protein-based adjuvants for vaccines as immunomodulators of the innate and adaptive immune response: Current knowledge, challenges, and future opportunities

DA Díaz-Dinamarca, ML Salazar, BN Castillo… - Pharmaceutics, 2022 - mdpi.com
New-generation vaccines, formulated with subunits or nucleic acids, are less immunogenic
than classical vaccines formulated with live-attenuated or inactivated pathogens. This …

Immune-modulating and anti-inflammatory marine compounds against cancer

C Florean, M Dicato, M Diederich - Seminars in Cancer Biology, 2022 - Elsevier
The recent advances in cancer immunotherapy confirm the crucial role of the immune
system in cancer progression and treatment. Chronic inflammation and reduced immune …

Investigating sources of conflict in deep phylogenomics of vetigastropod snails

TJ Cunha, JD Reimer, G Giribet - Systematic Biology, 2022 - academic.oup.com
Phylogenetic analyses may suffer from multiple sources of error leading to conflict between
genes and methods of inference. The evolutionary history of the mollusc clade …

Insights into Common Octopus (Octopus vulgaris) Ink Proteome and Bioactive Peptides Using Proteomic Approaches

MAS Imran, M Carrera, S Pérez-Polo, J Pérez, L Barros… - Marine Drugs, 2023 - mdpi.com
The common octopus (Octopus vulgaris) is nowadays the most demanded cephalopod
species for human consumption. This species was also postulated for aquaculture …

Immunotherapy: A new target for cancer cure

F Zhao, D Shen, M Shang, H Yu, X Zuo… - Oncology …, 2023 - spandidos-publications.com
Cancer is the leading cause of death globally and there is a worldwide cancer epidemic.
Immunotherapy has emerged as a promising anticancer therapy. In particular, oncolytic …

Antitumor Activity of Bioactive Compounds from Rapana venosa against Human Breast Cell Lines

M Petrova, Z Vlahova, M Schröder, J Todorova… - Pharmaceuticals, 2023 - mdpi.com
This study is the first report describing the promising antitumor activity of biologically active
compounds isolated from the hemolymph of marine snail Rapana venosa—a fraction with …

Immune induction by adjuvanted Leishmania donovani vaccines against the visceral leishmaniasis in BALB/c mice

DK Goyal, P Keshav, S Kaur - Immunobiology, 2021 - Elsevier
Visceral leishmaniasis (VL) is a neglected tropical disease caused by Leishmania donovani
or Leishmania infantum. Currently, the patients are treated with chemotherapeutic drugs; …