Brachytherapy future directions

JAM Cunha, R Flynn, C Bélanger, C Callaghan… - Seminars in radiation …, 2020 - Elsevier
Brachytherapy has advanced dramatically in the last decade due largely to improvements in
applicators, imaging, treatment planning, and use of clinical trials. In addition, current …

Guidelines by the AAPM and GEC‐ESTRO on the use of innovative brachytherapy devices and applications: Report of Task Group 167

R Nath, MJ Rivard, LA DeWerd, WA Dezarn… - Medical …, 2016 - Wiley Online Library
Although a multicenter, Phase III, prospective, randomized trial is the gold standard for
evidence‐based medicine, it is rarely used in the evaluation of innovative devices because …

A novel 169Yb‐based dynamic‐shield intensity modulated brachytherapy delivery system for prostate cancer

G Famulari, M Duclos, SA Enger - Medical physics, 2020 - Wiley Online Library
Purpose Intensity modulated brachytherapy (IMBT) is a novel high dose rate brachytherapy
(HDR BT) technique which incorporates static or dynamic shielding to increase tumor …

Microdosimetric evaluation of current and alternative brachytherapy sources—a Geant4-DNA simulation study

G Famulari, P Pater, SA Enger - International Journal of Radiation …, 2018 - Elsevier
Purpose Radioisotopes such as 75 Se, 169 Yb, and 153 Gd have photon energy spectra
and half-lives that make them excellent candidates as alternatives to 192 Ir for high-dose …

Interstitial rotating shield brachytherapy for prostate cancer

QE Adams, J Xu, EK Breitbach, X Li, SA Enger… - Medical …, 2014 - Wiley Online Library
Purpose: To present a novel needle, catheter, and radiation source system for interstitial
rotating shield brachytherapy (I‐RSBT) of the prostate. I‐RSBT is a promising technique for …

Monte Carlo dosimetry study of novel rotating MRI-compatible shielded tandems for intensity modulated cervix brachytherapy

M Morcos, SA Enger - Physica Medica, 2020 - Elsevier
Purpose Intensity modulated brachytherapy (IMBT) with rotating metal shields enables dose
modulation that can better conform to the tumor while reducing OAR doses. In this work, we …

Can intermediate-energy sources lead to elevated bone doses for prostate and head & neck high-dose-rate brachytherapy?

G Famulari, J Alfieri, M Duclos, T Vuong, SA Enger - Brachytherapy, 2020 - Elsevier
Purpose Several radionuclides with high (60 Co, 75 Se) and intermediate (169 Yb, 153 Gd)
energies have been investigated as alternatives to 192 Ir for high-dose-rate brachytherapy …

A novel direction modulated brachytherapy technique for urethra sparing in high-dose-rate brachytherapy of prostate cancer

M Meftahi, RLJ Qiu, P Patel, WY Song… - Radiotherapy and …, 2023 - Elsevier
Purpose Image-guided high-dose-rate (HDR) prostate brachytherapy is a safe and effective
treatment option for prostate cancer patients; however, some patients still experience acute …

Multisource rotating shield brachytherapy apparatus for prostate cancer

H Dadkhah, KM Hopfensperger, Y Kim, X Wu… - International Journal of …, 2017 - Elsevier
Purpose Our purpose is to present a novel multisource rotating shield brachytherapy (RSBT)
apparatus for the simultaneous precise angular and linear positioning of partially shielded …

Effectiveness of rotating shield brachytherapy for prostate cancer dose escalation and urethral sparing

Q Adams, KM Hopfensperger, Y Kim, X Wu… - International Journal of …, 2018 - Elsevier
Purpose To compare single-fraction 153 Gd-based rotating shield brachytherapy (RSBT) for
prostate cancer with conventional 192 Ir-based high-dose-rate brachytherapy (HDR-BT) in a …