[HTML][HTML] Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos

B Sripa, JM Bethony, P Sithithaworn, S Kaewkes… - Acta tropica, 2011 - Elsevier
Liver fluke infection caused by Opisthorchis viverrini is a major public health problem in
Thailand and the Lao People's Democratic Republic (Lao PDR; Laos). Currently, more than …

Food-borne trematodiases in Southeast Asia: epidemiology, pathology, clinical manifestation and control

B Sripa, S Kaewkes, PM Intapan, W Maleewong… - Advances in …, 2010 - Elsevier
The food-borne trematodiases are an important group of neglected tropical diseases
(NTDs). Over 40 million people are infected with food-borne trematodes and 750 million (> …

A Granulin-Like Growth Factor Secreted by the Carcinogenic Liver Fluke, Opisthorchis viverrini, Promotes Proliferation of Host Cells

MJ Smout, T Laha, J Mulvenna, B Sripa… - PLoS …, 2009 - journals.plos.org
The human liver fluke, Opisthorchis viverrini, infects millions of people throughout south-east
Asia and is a major cause of cholangiocarcinoma, or cancer of the bile ducts. The …

The draft genome of the carcinogenic human liver fluke Clonorchis sinensis

X Wang, W Chen, Y Huang, J Sun, J Men, H Liu, F Luo… - Genome biology, 2011 - Springer
Background Clonorchis sinensis is a carcinogenic human liver fluke that is widespread in
Asian countries. Increasing infection rates of this neglected tropical disease are leading to …

Similarities and differences among the Opisthorchiidae liver flukes: insights from Opisthorchis felineus

MY Pakharukova, VA Mordvinov - Parasitology, 2022 - cambridge.org
The foodborne liver trematode Opisthorchis felineus (Rivolta, 1884) is a member of the triad
of phylogenetically related epidemiologically important Opisthorchiidae trematodes, which …

Peroxiredoxin: a central player in immune modulation

MW Robinson, AT Hutchinson, JP Dalton… - Parasite …, 2010 - Wiley Online Library
Peroxiredoxins (Prx) are a family of anti‐oxidants that protect cells from metabolically
produced reactive oxygen species (ROS). The presence of these enzymes in the …

Peroxiredoxins in parasites

MC Gretes, LB Poole, PA Karplus - Antioxidants & redox signaling, 2012 - liebertpub.com
Significance: Parasite survival and virulence relies on effective defenses against reactive
oxygen and nitrogen species produced by the host immune system. Peroxiredoxins (Prxs) …

Parasitic helminths: a pharmacopeia of anti-inflammatory molecules

MJG Johnston, JA MacDonald, DM McKay - Parasitology, 2009 - cambridge.org
Infection with parasitic helminths takes a heavy toll on the health and well-being of humans
and their domestic livestock, concomitantly resulting in major economic losses. Analyses …

[HTML][HTML] Identification, genomic organization, and oxidative stress response of a sigma class glutathione S-transferase gene (AccGSTS1) in the honey bee, Apis …

H Yan, H Jia, H Gao, X Guo, B Xu - Cell Stress and Chaperones, 2013 - Elsevier
Glutathione S-transferases (GSTs) are members of a multifunctional antioxidant enzyme
superfamily that play pivotal roles in both detoxification and protection against oxidative …

Identification of potential inhibitors of Fasciola gigantica thioredoxin1: computational screening, molecular dynamics simulation, and binding free energy studies

R Shukla, H Shukla, P Kalita, A Sonkar… - Journal of …, 2018 - Taylor & Francis
Fasciola gigantica is the causative organism of fascioliasis and is responsible for major
economic losses in livestock production globally. F. gigantica thioredoxin1 (FgTrx1) is an …