Synthetic transporters for oxoanions

K Norvaisa, A Torres-Huerta, H Valkenier - Current opinion in chemical …, 2024 - Elsevier
This brief review highlights recent advances in the transport of oxoanions using synthetic
carriers, focusing on both progress and ongoing challenges in the field. The difficulty of …

[HTML][HTML] Tuning pH-dependent cytotoxicity in cancer cells by peripheral fluorine substitution on pseudopeptidic cages

L Tapia, Y Pérez, I Carreira-Barral, J Bujons… - Cell Reports Physical …, 2024 - cell.com
The acidic microenvironment of solid tumors is a potential source of selectivity in the anti-
cancer activity of ionophores, which requires delicate control of their biophysical properties …

Biomimetic ion channels: an emerging and promising material for therapeutic ion channelopathies

S Ren, Z Zhang, Z Dong - Trends in Chemistry, 2024 - cell.com
Aberrant ion channels are involved in the pathogenesis of various diseases; therefore,
targeting such channels represents a promising strategy for disease treatment. By mimicking …

Acylhydrazone-based reversibly photoswitchable ion pair transporter with OFF–ON cotransport activity

S Chattopadhayay, P Wanjari, P Talukdar - Chemical Science, 2024 - pubs.rsc.org
The cellular membrane transport of physiologically important cations and anions is
omnipresent and regulates different physiological functions. Whereas a notable number of …

Photo‐activation of Tolane‐based Synthetic Ion Channel for Transmembrane Chloride Transport

S Chattopadhayay, KV Banzal… - Angewandte Chemie, 2025 - Wiley Online Library
While natural channels respond to external stimuli to regulate ion concentration across cell
membranes, creating a synthetic version remains challenging. Here, we present a photo …

A unimolecular artificial cation channel based on cascaded hydrated acid groups

P Xin, H Yuan, L Zhang, Q Zhu, X Ning… - Journal of Materials …, 2024 - pubs.rsc.org
A cation channel possessing cascaded hydrated acid groups has been successfully
constructed using pillar [5] arene integrated with dual cyclodextrins. As a proof-of-concept …

Transmembrane Ion Channels: From Natural to Artificial Systems

T Yan, J Liu - Angewandte Chemie International Edition - Wiley Online Library
Natural channel proteins allow the selective permeation of ions, water or other nutritious
entities across bilayer membranes, facilitating various essential physiological functions in …