Our forefathers in pathology, on observing cancer tissue under the microscope in the mid-
19th century, noticed the similarity between embryonic tissue and cancer, and suggested …

This brief perspective article focuses on the most common errors and pitfalls, as well as the
do's and don'ts in drug combination studies, in terms of experimental design, data …

When designing drug carriers, the drug-to-carrier ratio is an important consideration,
because the use of high quantities of carriers can result in toxicity as a consequence of poor …

US9040574B2 - Method of treating androgen independent prostate cancer - Google Patents
US9040574B2 - Method of treating androgen independent prostate cancer - Google Patents …

This brief article focuses on two aims: i) To investigate the in vitro pharmaco-dynamic
interactions of combining synthetic potent microtubule targeting anticancer agent, Fludelone …

Background The systemic administration of cytotoxic chemotherapeutic agents for cancer
treatment often has toxic side effects, limiting the usage dose. To increase chemotherapeutic …

The present study was carried out to evaluate the possible synergistic interactions on
antibacterial and antioxidant efficacy of essential oils of some selected spices and herbs …

Development of multidrug resistance (MDR) against a variety of conventional and novel
chemotherapeutic agents is a significant challenge in effective cancer therapy. Over the last …

Combinatorial control of biological processes, in which redundancy and multifunctionality
are the norm, fundamentally limits the therapeutic index that can be achieved by even the …

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a redox-sensitive transcription factor
regulating the expression of a battery of cytoprotective genes. Constitutive Nrf2 activation in …