Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research

F Hufsky, K Lamkiewicz, A Almeida… - Briefings in …, 2021 - academic.oup.com
Abstract SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of
the family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of …

Divergent SARS-CoV-2 variant emerges in white-tailed deer with deer-to-human transmission

B Pickering, O Lung, F Maguire, P Kruczkiewicz… - Nature …, 2022 - nature.com
Wildlife reservoirs of broad-host-range viruses have the potential to enable evolution of viral
variants that can emerge to infect humans. In North America, there is phylogenomic …

A survey on the algorithm and development of multiple sequence alignment

Y Zhang, Q Zhang, J Zhou, Q Zou - Briefings in bioinformatics, 2022 - academic.oup.com
Multiple sequence alignment (MSA) is an essential cornerstone in bioinformatics, which can
reveal the potential information in biological sequences, such as function, evolution and …

RNA genome conservation and secondary structure in SARS-CoV-2 and SARS-related viruses: a first look

R Rangan, IN Zheludev, RJ Hagey, EA Pham… - Rna, 2020 - rnajournal.cshlp.org
As the COVID-19 outbreak spreads, there is a growing need for a compilation of conserved
RNA genome regions in the SARS-CoV-2 virus along with their structural propensities to …

Highly divergent white-tailed deer SARS-CoV-2 with potential deer-to-human transmission

B Pickering, O Lung, F Maguire, P Kruczkiewicz… - BioRxiv, 2022 - biorxiv.org
Wildlife reservoirs of SARS-CoV-2 can lead to viral adaptation and spillback from wildlife to
humans. In North America, there is evidence of spillover of SARS-CoV-2 from humans to …

ViralMSA: Massively scalable reference-guided multiple sequence alignment of viral genomes

N Moshiri - Bioinformatics, 2021 - academic.oup.com
Motivation In molecular epidemiology, the identification of clusters of transmissions typically
requires the alignment of viral genomic sequence data. However, existing methods of …

A computational method for the identification of Dengue, Zika and Chikungunya virus species and genotypes

V Fonseca, PJK Libin, K Theys, NR Faria… - PLoS neglected …, 2019 - journals.plos.org
In recent years, an increasing number of outbreaks of Dengue, Chikungunya and Zika
viruses have been reported in Asia and the Americas. Monitoring virus genotype diversity is …

SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts

RN Tasakis, G Samaras, A Jamison, M Lee, A Paulus… - PLoS …, 2021 - journals.plos.org
Since the first case of COVID-19 in December 2019 in Wuhan, China, SARS-CoV-2 has
spread worldwide and within a year and a half has caused 3.56 million deaths globally. With …

Mapping the dynamics of contemporary PRRSV-2 evolution and its emergence and spreading hotspots in the US using phylogeography

N Pamornchainavakul, IAD Paploski, DN Makau… - Pathogens, 2023 - mdpi.com
The repeated emergence of new genetic variants of PRRSV-2, the virus that causes porcine
reproductive and respiratory syndrome (PRRS), reflects its rapid evolution and the failure of …

Atypical divergence of SARS-CoV-2 Orf8 from Orf7a within the coronavirus lineage suggests potential stealthy viral strategies in immune evasion

RY Neches, NC Kyrpides, CA Ouzounis - MBio, 2021 - Am Soc Microbiol
Orf8, one of the most puzzling genes in the SARS lineage of coronaviruses, marks a unique
and striking difference in genome organization between SARS-CoV-2 and SARS-CoV-1 …