Nanodrug Delivery Strategies to Signaling Pathways in Alopecia

X Wu, Y Du - Molecular Pharmaceutics, 2023 - ACS Publications
Over 50% of the global population suffers from hair loss. The mixed results in the treatment
of hair loss reveal the limitations of conventional commercial topical drugs. One the one …

Sulforaphane diminishes moonlighting of pyruvate kinase M2 and interleukin 1β expression in M1 (LPS) macrophages

S Bahiraii, M Brenner, F Yan, W Weckwerth… - Frontiers in …, 2022 - frontiersin.org
Murine macrophages activated by the Toll-like receptor 4 agonist lipopolysaccharide (LPS)
polarize to the M1 type by inducing proinflammatory marker proteins and changing their …

The Role of Macrophages in Cardiac Function and Disease

N Prevete, D Sorriento - Journal of Molecular Pathology, 2023 - mdpi.com
A tight association between inflammation and cardiac damage has been extensively
recognized. In this review, we will focus on macrophages as key players in the physiology …

Mitochondrial function in macrophages controls cardiac repair after myocardial infarction

D Weissman, C Maack - The Journal of clinical investigation, 2023 - Am Soc Clin Investig
Cardiac healing following acute myocardial infarction (MI) involves the mobilization and
activation of immune cells, including macrophages. In the early phase after MI …

[HTML][HTML] Itaconic acid facilitates inflammation abatement and alleviates liver ischemia-reperfusion injury by inhibiting NF-κB/NLRP3/caspase-1 inflammasome axis

E Ma, H Xing, J Pei, Q Zhang, R Li, C Shen… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Ischemia-reperfusion injury (IRI) severely limits the efficacy and donor source of
liver transplantation, and the crucial step in alleviating it is to control inflammation. Itaconic …

Sr-Incorporated Bioactive Glass Remodels the Immunological Microenvironment by Enhancing the Mitochondrial Function of Macrophage via the PI3K/AKT/mTOR …

H Qiu, H Xiong, J Zheng, Y Peng, C Wang… - ACS Biomaterials …, 2024 - ACS Publications
The repair of critical-sized bone defects continues to pose a challenge in clinics. Strontium
(Sr), recognized for its function in bone metabolism regulation, has shown potential in bone …

The Imbalance of Mitochondrial Homeostasis of Peripheral Blood‐Derived Macrophages Mediated by MAFLD May Impair the Walking Ability of Elderly Patients with …

X Wang, X Liu, P He, K Guan, Y Yang… - Oxidative Medicine …, 2022 - Wiley Online Library
Introduction. Many Asian cohort studies have shown that nonalcoholic fatty liver disease
(NAFLD), now renamed as metabolic dysfunction‐associated fatty liver disease (MAFLD) …

A novel quinoline with airway relaxant effects and anti-inflammatory properties

J Bergwik, J Liu, M Padra, RKV Bhongir, L Tanner… - Respiratory …, 2024 - Springer
Background In chronic pulmonary diseases characterized by inflammation and airway
obstruction, such as asthma and COPD, there are unmet needs for improved treatment …

IL-1 signaling pathway, an important target for inflammation surrounding in myocardial infarction

J Huang, W Kuang, Z Zhou - Inflammopharmacology, 2024 - Springer
Acute myocardial infarction is an important cardiovascular disease worldwide. Although the
mortality rate of myocardial infarction (MI) has improved dramatically in recent years due to …

Mitochondrial Metabolism in Alveolar Macrophages of Patients Infected with HIV, Tuberculosis, and HIV/Tuberculosis

L Zhang, M Cai, B Su, Y Ma, Y Zhang - AIDS Research and Human …, 2024 - liebertpub.com
Tuberculosis (TB) is one of the most common opportunistic infections and is a leading cause
of mortality in patients with HIV and AIDS. HIV infection causes serious defects in the host …