Background: Optimization of postoperative outcome requires the application of evidence-
based principles of care carefully integrated into a multimodal rehabilitation program …

The state of wound oxygenation is a key determinant of healing outcomes. From a
diagnostic standpoint, measurements of wound oxygenation are commonly used to guide …

EXECUTIVE SUMMARY OF THE GUIDELINE Philosophy of the guideline c Oxygen is a
treatment for hypoxaemia, not breathlessness.(Oxygen has not been shown to have any …

Context Use of 80% oxygen during surgery has been suggested to reduce the risk of
surgical wound infections, but this effect has not been consistently identified. The effect of …

Introduction Colorectal anastomotic leak, a feared complication, results in significantly
increased patient morbidity, mortality, and hospital resource utilization. The overall …

Background Colorectal anastomotic leakage (CAL) is a major surgical complication in
intestinal surgery. Despite many optimizations in patient care, the incidence of CAL is stable …

Background Available evidence on the effects of a high fraction of inspired oxygen (FIO 2) of
60% to 90% compared with a routine fraction of inspired oxygen of 30% to 40%, during …

In 1887, William Halsted wrote:“The death-rate attending enterorrhaphy has been large,
and, in general, the operation, even in the hands of the most skillful surgeons, has been …

Objective To examine whether supraphysiological oxygen administration during surgery is
associated with lower or higher postoperative kidney, heart, and lung injury. Design …

Objective To assess the influence of hyperoxygenation on surgical site infection by using the
most homogeneous study population. Design A randomized, prospective, controlled trial …