The potential of using blood circular RNA as liquid biopsy biomarker for human diseases

G Wen, T Zhou, W Gu - Protein & cell, 2021 - academic.oup.com
Circular RNA (circRNA) is a novel class of single-stranded RNAs with a closed loop
structure. The majority of circRNAs are formed by a back-splicing process in pre-mRNA …

Non-coding RNAs in rheumatoid arthritis: from bench to bedside

J Wang, S Yan, J Yang, H Lu, D Xu… - Frontiers in immunology, 2020 - frontiersin.org
Rheumatoid arthritis is a common systemic and autoimmune disease characterized by
symmetrical and inflammatory destruction of distal joints. Its primary pathological characters …

[HTML][HTML] CircRNA Cdr1as functions as a competitive endogenous RNA to promote hepatocellular carcinoma progression

Y Su, X Lv, W Yin, L Zhou, Y Hu, A Zhou, FZ Qi - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide.
Recent years, circular RNA (circRNA) have been shown to exert vital functions in the …

[HTML][HTML] Circular RNA circLMO1 suppresses cervical cancer growth and metastasis by triggering miR-4291/ACSL4-mediated ferroptosis

R Ou, S Lu, L Wang, Y Wang, M Lv, T Li, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Background: A number of studies have demonstrated that circular RNA (circRNA) plays a
critical role in tumorigenesis and tumor progression. However, the biological effects of most …

circRNAs signature as potential diagnostic and prognostic biomarker for diabetes mellitus and related cardiovascular complications

M Zaiou - Cells, 2020 - mdpi.com
Circular RNAs (circRNAs) belong to the ever-growing class of naturally occurring noncoding
RNAs (ncRNAs) molecules. Unlike linear RNA, circRNAs are covalently closed transcripts …

Targeting the androgen receptor to enhance NK cell killing efficacy in bladder cancer by modulating ADAR2/circ_0001005/PD-L1 signaling

Q Liu, B You, J Meng, CP Huang, G Dong… - Cancer Gene …, 2022 - nature.com
Although androgen receptor (AR) can influence bladder cancer (BCa) initiation and
progression, its impact on tumor immune escape remains unclear. Here, we found that …

Circular RNA circSLC25A16 contributes to the glycolysis of non-small-cell lung cancer through epigenetic modification

H Shangguan, H Feng, D Lv, J Wang, T Tian… - Cell Death & …, 2020 - nature.com
Growing evidence has highlighted the roles of circular RNAs (circRNAs) in non-small-cell
lung cancer (NSCLC), however, their roles in NSCLC glycolysis remains poorly understood …

CREBZF mRNA nanoparticles suppress breast cancer progression through a positive feedback loop boosted by circPAPD4

B Zhou, J Xue, R Wu, H Meng, R Li, Z Mo… - Journal of Experimental …, 2023 - Springer
Background Breast cancer (BC) negatively impacts the health of women worldwide. Circular
RNAs (circRNAs) are a group of endogenous RNAs considered essential regulatory factor in …

The emerging value of circular noncoding RNA research in cancer diagnosis and treatment

U Jagtap, ES Anderson, FJ Slack - Cancer research, 2023 - AACR
Circular RNAs (circRNA) are a recently described class of RNA molecules that have
attracted substantial attention as new components of disease mechanisms and as potential …

Circular RNAs in sepsis: biogenesis, function, and clinical significance

J Beltran-Garcia, R Osca-Verdegal, E Nacher-Sendra… - Cells, 2020 - mdpi.com
Sepsis is a life-threatening condition that occurs when the body responds to an infection that
damages it is own tissues. The major problem in sepsis is rapid, vital status deterioration in …