The molecular basis of herpes simplex virus latency

MP Nicoll, JT Proença… - FEMS microbiology …, 2012 - academic.oup.com
Herpes simplex virus type 1 is a neurotropic herpesvirus that establishes latency within
sensory neurones. Following primary infection, the virus replicates productively within …

The viral and cellular microRNA targetome in lymphoblastoid cell lines

RL Skalsky, DL Corcoran, E Gottwein, CL Frank… - PLoS …, 2012 - journals.plos.org
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell
cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral …

Exosomes derived from HIV-1-infected cells contain trans-activation response element RNA

A Narayanan, S Iordanskiy, R Das, R Van Duyne… - Journal of Biological …, 2013 - ASBMB
Exosomes are nano-sized vesicles produced by healthy and virus-infected cells. Exosomes
derived from infected cells have been shown to contain viral microRNAs (miRNAs). HIV-1 …

EBV and human microRNAs co‐target oncogenic and apoptotic viral and human genes during latency

KJ Riley, GS Rabinowitz, TA Yario, JM Luna… - The EMBO …, 2012 - embopress.org
Epstein–Barr virus (EBV) controls gene expression to transform human B cells and maintain
viral latency. High‐throughput sequencing and crosslinking immunoprecipitation (HITS …

Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq

JD Khoury, NM Tannir, MD Williams, Y Chen… - Journal of …, 2013 - Am Soc Microbiol
Elucidation of tumor-DNA virus associations in many cancer types has enhanced our
knowledge of fundamental oncogenesis mechanisms and provided a basis for cancer …

KSHV LANA—the master regulator of KSHV latency

T Uppal, S Banerjee, Z Sun, SC Verma, ES Robertson - Viruses, 2014 - mdpi.com
Kaposi's sarcoma associated herpesvirus (KSHV), like other human herpes viruses,
establishes a biphasic life cycle referred to as dormant or latent, and productive or lytic …

An identical miRNA of the human JC and BK polyoma viruses targets the stress-induced ligand ULBP3 to escape immune elimination

Y Bauman, D Nachmani, A Vitenshtein, P Tsukerman… - Cell host & …, 2011 - cell.com
The human polyoma viruses JCV and BKV establish asymptomatic persistent infection in
65%–90% of humans but can cause severe illness under immunosuppressive conditions …

Systemically circulating viral and tumor-derived microRNAs in KSHV-associated malignancies

PE Chugh, SH Sin, S Ozgur, DH Henry… - PLoS …, 2013 - journals.plos.org
MicroRNAs (miRNAs) are stable, small non-coding RNAs that modulate many downstream
target genes. Recently, circulating miRNAs have been detected in various body fluids and …

Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas

I Haecker, LA Gay, Y Yang, J Hu, AM Morse… - 2012 - journals.plos.org
KSHV is the etiological agent of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL),
and a subset of multicentricCastleman's disease (MCD). The fact that KSHV-encoded …

MicroRNAs and exosomes: key players in HIV pathogenesis

J Sadri Nahand, F Bokharaei‐Salim… - HIV …, 2020 - Wiley Online Library
Objectives HIV infection is well known to cause impairment of the human immune system,
and until recently was a leading cause of death. It has been shown that T lymphocytes are …