Biochemical verification of tobacco use and abstinence: 2019 update

NL Benowitz, JT Bernert, J Foulds… - Nicotine and …, 2020 - academic.oup.com
Background The changing prevalence and patterns of tobacco use, the advent of novel
nicotine delivery devices, and the development of new biomarkers prompted an update of …

Tobacco carcinogens, their biomarkers and tobacco-induced cancer

SS Hecht - Nature Reviews Cancer, 2003 - nature.com
The devastating link between tobacco products and human cancers results from a powerful
alliance of two factors—nicotine and carcinogens. Without either one of these, tobacco …

Air pollution combustion emissions: characterization of causative agents and mechanisms associated with cancer, reproductive, and cardiovascular effects

J Lewtas - Mutation Research/Reviews in Mutation Research, 2007 - Elsevier
Combustion emissions account for over half of the fine particle (PM2. 5) air pollution and
most of the primary particulate organic matter. Human exposure to combustion emissions …

Cigarette smoking and lung cancer: chemical mechanisms and approaches to prevention

SS Hecht - The lancet oncology, 2002 - thelancet.com
Much is now known about the carcinogens in cigarette smoke, their conversion to forms that
react with DNA, and the miscoding properties of the resulting DNA adducts that cause the …

Assessing secondhand smoke using biological markers

E Avila-Tang, WK Al-Delaimy, DL Ashley… - Tobacco …, 2013 - tobaccocontrol.bmj.com
Secondhand smoke exposure (SHSe) is a known cause of many adverse health effects in
adults and children. Increasingly, SHSe assessment is an element of tobacco control …

Human urinary carcinogen metabolites: biomarkers for investigating tobacco and cancer

SS Hecht - Carcinogenesis, 2002 - academic.oup.com
Measurement of human urinary carcinogen metabolites is a practical approach for obtaining
important information about tobacco and cancer. This review presents currently available …

Environmental tobacco smoke and risk of respiratory cancer and chronic obstructive pulmonary disease in former smokers and never smokers in the EPIC prospective …

P Vineis, L Airoldi, F Veglia, L Olgiati, R Pastorelli… - Bmj, 2005 - bmj.com
Objectives To investigate the association between environmental tobacco smoke, plasma
cotinine concentration, and respiratory cancer or death. Design Nested case-control study …

Progress and challenges in selected areas of tobacco carcinogenesis

SS Hecht - Chemical research in toxicology, 2008 - ACS Publications
Tobacco use continues to be a major cause of cancer in the developed world, and despite
significant progress in this country in tobacco control, which is driving a decrease in cancer …

IARC monographs on the evaluation of carcinogenic risks to humans

AJ Zuckerman - Journal of Clinical Pathology, 1995 - pmc.ncbi.nlm.nih.gov
Viral hepatitis in all its forms is a major public health problem throughout the world, affecting
several hundreds of millions of people. Viral hepatitis is a cause of considerable morbidity …

Exposure and metabolic activation biomarkers of carcinogenic tobacco-specific nitrosamines

SS Hecht, I Stepanov, SG Carmella - Accounts of chemical …, 2016 - ACS Publications
Conspectus Lung cancer is the leading cause of cancer death in the world, and cigarette
smoking is its main cause. Oral cavity cancer is another debilitating and often fatal cancer …