Spatial navigation and memory: A review of the similarities and differences relevant to brain models and age

AD Ekstrom, PF Hill - Neuron, 2023 - cell.com
Spatial navigation and memory are often seen as heavily intertwined at the cognitive and
neural levels of analysis. We review models that hypothesize a central role for the medial …

Age differences in retrieval-related reinstatement reflect age-related dedifferentiation at encoding

PF Hill, DR King, MD Rugg - Cerebral Cortex, 2021 - academic.oup.com
Age-related reductions in neural selectivity have been linked to cognitive decline. We
examined whether age differences in the strength of retrieval-related cortical reinstatement …

The retrieval-related anterior shift is moderated by age and correlates with memory performance

S Srokova, PF Hill, MD Rugg - Journal of Neuroscience, 2022 - Soc Neuroscience
Recent research suggests that episodic memory is associated with systematic differences in
the localization of neural activity observed during memory encoding and retrieval. The …

Age differences in neural distinctiveness during memory encoding, retrieval, and reinstatement

C Pauley, M Kobelt, M Werkle-Bergner… - Cerebral …, 2023 - academic.oup.com
Robust evidence points to mnemonic deficits in older adults related to dedifferentiated, ie
less distinct, neural responses during memory encoding. However, less is known about …

Tracking age differences in neural distinctiveness across representational levels

M Kobelt, VR Sommer, A Keresztes… - Journal of …, 2021 - Soc Neuroscience
The distinctiveness of neural information representation is crucial for successful memory
performance but declines with advancing age. Computational models implicate age-related …

Dissociative effects of age on neural differentiation at the category and item levels

S Srokova, ANZ Aktas, JD Koen… - Journal of …, 2024 - Soc Neuroscience
Increasing age is associated with age-related neural dedifferentiation, a reduction in the
selectivity of neural representations, which has been proposed to contribute to cognitive …

Greater neural differentiation in the ventral visual cortex is associated with youthful memory in superaging

Y Katsumi, JM Andreano, LF Barrett… - Cerebral …, 2021 - academic.oup.com
Superagers are older adults who maintain youthful memory despite advanced age. Previous
studies showed that superagers exhibit greater structural and intrinsic functional brain …

Representing the Good and Bad: fMRI signatures during the encoding of multisensory positive, negative, and neutral events

PP Thakral, R Bottary, EA Kensinger - Cortex, 2022 - Elsevier
Few studies have examined how multisensory emotional experiences are processed and
encoded into memory. Here, we aimed to determine whether, at encoding, activity within …

Age-related neural dedifferentiation for individual stimuli: An across-participant pattern similarity analysis

JD Koen - Aging, Neuropsychology, and Cognition, 2022 - Taylor & Francis
Age-related neural dedifferentiation–reductions in the regional specificity and precision of
neural representations–is proposed to compromise the ability of older adults to form …

Increased neural differentiation after a single session of aerobic exercise in older adults

J Purcell, R Wiley, J Won, D Callow, L Weiss… - Neurobiology of …, 2023 - Elsevier
Aging is associated with decreased cognitive function. One theory posits that this decline is
in part due to multiple neural systems becoming dedifferentiated in older adults. Exercise is …