The glycoprotein follicle-stimulating hormone (FSH) acts on gonadal target cells, hence
regulating gametogenesis. The transduction of the hormone-induced signal is mediated by …

Vitamin D is a versatile signalling molecule with a well-established role in the regulation of
calcium homeostasis and bone health. The spectrum of vitamin D target organs has …

Calcium (Ca2+) can regulate a wide variety of cellular fates, such as proliferation, apoptosis,
and autophagy. More importantly, changes in the intracellular Ca2+ level can modulate …

Context: The vitamin D system has pleiotropic effects not only in bone metabolism. Its role in
testicular steroidogenesis is new and deserves intensive research. Objective: We …

In the gonads and adrenal glands, the transient increase in steroidogenesis after hormonal
stimulation requires modulation of steroidogenic acute regulatory protein (Star) expression …

Endoplasmic reticulum (ER) stress generally occurs in secretory cell types. It has been
reported that Leydig cells, which produce testosterone in response to human chorionic …

Casein kinase 1α (CK1α) is a main component of the Wnt/β-catenin signaling pathway,
which participates in multiple biological processes. Our recent study demonstrated that …

Objective Vitamin D status has been associated with sex steroid production. The question is
whether vitamin D supplementation has an impact on sex steroid production in infertile men …

Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) control antral follicular
growth by regulating several processes, such as the synthesis of hormones and signaling …

In this review, we describe the current knowledge on calcium signaling pathways in
interstitial cells with a special focus on interstitial cells of Cajal (ICCs), interstitial Cajal-like …