Atherosclerosis, a chronic multifactorial disease, is closely related to the development of
cardiovascular diseases and is one of the predominant causes of death worldwide. Normal …

Parkinson's disease (PD) is one of the most common degenerative brain disorders caused
by the loss of dopaminergic neurons in the substantia nigra (SN). Lewy bodies and …

Homocysteine (Hcy) is an amino acid involved in gene methylation. Plasma concentration of
Hcy is elevated in the pathological condition hyperhomocysteinemia (HHcy), which …

Parkinson's disease (PD) is the second most common age-associated neurodegenerative
disorder and is characterised by progressive loss of dopamine neurons in the substantia …

The purpose of the present study was to investigate whether catalpol exhibited
neuroprotective effects in chronic unpredictable mild stress (CUMS) mice through oxidative …

Context The effect of kaempferol, a regulator of oestrogen receptors, on atherosclerosis (AS)
and the underlying mechanism is elusive. Objective To explore the effect and mechanism of …

Preclinical studies have shown that the gut microbiota can play a role in schizophrenia
(SCH) pathogenesis via the gut-brain axis. However, its role in the antipsychotic treatment …

Ethnopharmacological relevance Atherosclerosis (AS) is a common systemic disease with
increasing morbidity and mortality worldwide. Traditional Chinese medicine (TCM) with …

The traditional Chinese medicine (TCM) Rehmanniae Radix (RR) refers to the fresh or dried
root tuber of the plant Rehmannia glutinosa Libosch of the family Scrophulariaceae. As a …

Catalpol, an iridoid glucoside, is widely distributed in many plant families and is primarily
obtained from the root of Rehmannia glutinosa Libosch. Rehmannia glutinosa is a plant very …