The real-time, dynamic optical visualization of lesions and margins ensures not only
complete resection of the malignant tissues but also better preservation of the vital …

The phospholipase A2 (PLA2) superfamily of phospholipase enzymes hydrolyzes the ester
bond at the sn-2 position of the phospholipids, generating a free fatty acid and a …

Intraoperative molecular imaging (IMI) has recently emerged as an important tool in the
armamentarium of surgical oncologists. IMI allows real-time assessment of oncologic …

Serine hydrolases (SHs) comprise a large family of hydrolytic enzymes that play crucial roles
in numerous physiological and pathological processes, such as blood coagulation, cancer …

Abstract The WMIS Education Committee (2019–2022) reached a consensus that white
papers on molecular imaging could be beneficial for practitioners of molecular imaging at …

New exogenous probes are needed for both imaging diagnostics and therapeutics. Here,
we introduce a novel nanocomposite near-infrared (NIR) fluorescent imaging probe and test …

Arachidonic acid (AA) is a phospholipase A2 metabolite that has been reported to mediate a
plethora of cellular mechanisms involved in healthy and pathological states such as platelet …

Several studies reported a central role of the endothelin type A receptor (ETAR) in tumor
progression leading to the formation of metastasis. Here, we investigated the in vitro and in …

Accurate and timely assessment of malignant tumors in the early stage and therapy process
is critical for making clear guidance and prognosis for the treatment, which can significantly …

Breast cancer is the most common malignancy in women and is a heterogeneous disease at
molecular level. Early detection and specificity are the key prerequisite for the treatment of …