Thromboembolic and bleeding events in transthyretin amyloidosis and coagulation system abnormalities: a review

A Napolitano, L De Michieli, G Sinigiani… - Journal of Clinical …, 2023 - mdpi.com
Transthyretin amyloidosis (ATTR) is a group of diseases caused by the deposition of
insoluble fibrils derived from misfolded transthyretin, which compromises the structure and …

Thromboembolic and Bleeding Risk in Cardiac Amyloidosis

M Tana, C Tana, D Rossi, C Mantini, S Gallina… - Journal of Thrombosis …, 2024 - Elsevier
Cardiac amyloidosis represents a spectrum of conditions characterized by the accumulation
of insoluble fibrils, resulting in progressive deposition and myocardial dysfunction. The exact …

Impact of anemia on mortality and morbidity in transthyretin amyloid cardiomyopathy

A Wardhere, D Bampatsias, A Mirabal-Santos… - The American Journal of …, 2024 - Elsevier
Anemia is prevalent in transthyretin amyloid cardiomyopathy (ATTR-CM), but its prognostic
significance remains uncertain because of conflicting data mainly in patients not receiving …

The discovery and development of transthyretin amyloidogenesis inhibitors: what are the lessons?

B Zhong, X Huang, Y Zheng, X Guo… - Future Medicinal …, 2021 - Taylor & Francis
Transthyretin (TTR) is associated with several human amyloid diseases. Various kinetic
stabilizers have been developed to inhibit the dissociation of TTR tetramer and the formation …

[HTML][HTML] A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels

N Javed, K Uday - Cureus, 2023 - ncbi.nlm.nih.gov
The prevalence of light chain (AL) amyloidosis, characterized by the deposition of amyloid
chains, is gradually increasing. The clinical features of the disease depend upon the …

[HTML][HTML] Gross hematuria: An unusual presenting symptom of systemic wild-type transthyretin amyloidosis

SA Vincent, D Christensen, PR Weiner - Urology Case Reports, 2021 - Elsevier
Amyloidosis of the urinary bladder is a rare cause of gross hematuria. In patients with
systemic amyloidosis, identification is nearly always related to cardiac complaints; urologic …