A systematic review of childhood maltreatment and DNA methylation: candidate gene and epigenome-wide approaches
Childhood maltreatment is a major risk factor for chronic and severe mental and physical
health problems across the lifespan. Increasing evidence supports the hypothesis that …
health problems across the lifespan. Increasing evidence supports the hypothesis that …
Adverse childhood events and health biomarkers: a systematic review
Background: This systematic review aimed to summarize evidence reporting epigenetic
and/or neuro-immuno-endocrine embedding of adverse childhood events (ACEs) in …
and/or neuro-immuno-endocrine embedding of adverse childhood events (ACEs) in …
The behavioural constellation of deprivation: Causes and consequences
Socioeconomic differences in behaviour are pervasive and well documented, but their
causes are not yet well understood. Here, we make the case that a cluster of behaviours is …
causes are not yet well understood. Here, we make the case that a cluster of behaviours is …
Sensitive periods for the effect of childhood adversity on DNA methylation: results from a prospective, longitudinal study
Background Exposure to early-life adversity is known to predict DNA methylation (DNAm)
patterns that may be related to psychiatric risk. However, few studies have investigated …
patterns that may be related to psychiatric risk. However, few studies have investigated …
Analysis of DNA methylation in young people: limited evidence for an association between victimization stress and epigenetic variation in blood
Objective: DNA methylation has been proposed as an epigenetic mechanism by which early-
life experiences become “embedded” in the genome and alter transcriptional processes to …
life experiences become “embedded” in the genome and alter transcriptional processes to …
Annual Research Review: DNA methylation as a mediator in the association between risk exposure and child and adolescent psychopathology
Background DNA methylation (DNAm) is a potential mechanism for propagating the effects
of environmental exposures on child and adolescent mental health. In recent years, this field …
of environmental exposures on child and adolescent mental health. In recent years, this field …
Social and physical environments early in development predict DNA methylation of inflammatory genes in young adulthood
Chronic inflammation contributes to a wide range of human diseases, and environments in
infancy and childhood are important determinants of inflammatory phenotypes. The …
infancy and childhood are important determinants of inflammatory phenotypes. The …
Epigenetic correlates of neonatal contact in humans
Animal models of early postnatal mother–infant interactions have highlighted the importance
of tactile contact for biobehavioral outcomes via the modification of DNA methylation …
of tactile contact for biobehavioral outcomes via the modification of DNA methylation …
DNA methylation as a predictor of fetal alcohol spectrum disorder
AA Lussier, AM Morin, JL MacIsaac, J Salmon… - Clinical …, 2018 - Springer
Background Fetal alcohol spectrum disorder (FASD) is a developmental disorder that
manifests through a range of cognitive, adaptive, physiological, and neurobiological deficits …
manifests through a range of cognitive, adaptive, physiological, and neurobiological deficits …
An investigation of child maltreatment and epigenetic mechanisms of mental and physical health risk
In the present investigation, differential methylation analyses of the whole genome were
conducted among a sample of 548 school-aged low-income children (47.8% female, 67.7 …
conducted among a sample of 548 school-aged low-income children (47.8% female, 67.7 …