The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity

N Lehnert, E Kim, HT Dong, JB Harland… - Chemical …, 2021 - ACS Publications
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Thiol-based redox switches in prokaryotes

M Hillion, H Antelmann - Biological chemistry, 2015 - degruyter.com
Bacteria encounter reactive oxygen species (ROS) as a consequence of the aerobic life or
as an oxidative burst of activated neutrophils during infections. In addition, bacteria are …

Upgrade the high-load anaerobic digestion and relieve acid stress through the strategy of side-stream micro-aeration: biochemical performances, microbial response …

W Li, Y Liu, B Wu, L Gu, R Deng - Water Research, 2022 - Elsevier
In high-load anaerobic digestion such as in kitchen waste, side-stream micro-aeration (SMA)
shows excellent operational performance to direct micro-aeration (DMA). It immediately …

Responses of Clostridia to oxygen: from detoxification to adaptive strategies

C Morvan, F Folgosa, N Kint, M Teixeira… - Environmental …, 2021 - Wiley Online Library
Clostridia comprise bacteria of environmental, biotechnological and medical interest and
many commensals of the gut microbiota. Because of their strictly anaerobic lifestyle, oxygen …

An anaerobic bacterium, Bacteroides thetaiotaomicron, uses a consortium of enzymes to scavenge hydrogen peroxide

S Mishra, JA Imlay - Molecular microbiology, 2013 - Wiley Online Library
Obligate anaerobes are periodically exposed to oxygen, and it has been conjectured that on
such occasions their low‐potential biochemistry will predispose them to rapid ROS …

The nitric oxide reductase mechanism of a flavo-diiron protein: identification of active-site intermediates and products

JD Caranto, A Weitz, MP Hendrich… - Journal of the American …, 2014 - ACS Publications
The unique active site of flavo-diiron proteins (FDPs) consists of a nonheme diiron-
carboxylate site proximal to a flavin mononucleotide (FMN) cofactor. FDPs serve as the …

How superoxide reductases and flavodiiron proteins combat oxidative stress in anaerobes

MC Martins, CV Romão, F Folgosa, PT Borges… - Free Radical Biology …, 2019 - Elsevier
Microbial anaerobes are exposed in the natural environment and in their hosts, even if
transiently, to fluctuating concentrations of oxygen and its derived reactive species, which …

Insights into the nitric oxide reductase mechanism of flavodiiron proteins from a flavin-free enzyme

T Hayashi, JD Caranto, DA Wampler, DM Kurtz Jr… - Biochemistry, 2010 - ACS Publications
Flavodiiron proteins (FDPs) catalyze reductive scavenging of dioxygen and nitric oxide in air-
sensitive microorganisms. FDPs contain a distinctive non-heme diiron/flavin mononucleotide …

The dual function of flavodiiron proteins: oxygen and/or nitric oxide reductases

CV Romão, JB Vicente, PT Borges, C Frazão… - JBIC Journal of …, 2016 - Springer
Flavodiiron proteins have emerged in the last two decades as a newly discovered family of
oxygen and/or nitric oxide reductases widespread in the three life domains, and present in …

Redox-responsive repressor Rex modulates alcohol production and oxidative stress tolerance in Clostridium acetobutylicum

L Zhang, X Nie, DA Ravcheev, DA Rodionov… - Journal of …, 2014 - Am Soc Microbiol
Rex, a transcriptional repressor that modulates its DNA-binding activity in response to
NADH/NAD+ ratio, has recently been found to play a role in the solventogenic shift of …